|
|
|||
|
||||
OverviewHow does the chemical description of a protein relate to its three-dimensional structure? How does the three-dimensional structure relate to the machinery that brings about a chemical reaction? How does the sequence of a gene encode not only the sequence of a protein but, more importantly, the architecture and function of that protein?Protein Structure and Function provides a clear and critical survey of our current understanding of the structure and function of proteins to answer questions such as these. Opening with a consideration of the link between protein sequence and structure, it goes on to explore the structural basis of protein function and how this function is controlled. Finally, it examines a range of case studies that illuminate the range of roles performed by proteins, and the diverse structures these proteins exhibit.Protein Structure and Function combines articulate prose with striking full colour illustrations, while the unique Primers in Biology modular structure integrates text, illustrations, definitions, and literature references for each topic into one double-page spread, bringing to the student's fingertips all the tools that they need to master that topic.Online Resource Centre The Online Resource Centre features figures from the book available to download, for registered adopters of the book. Full Product DetailsAuthor: Gregory A. Petsko (Director of the Rosentiel Center, Brandeis University) , Dagmar Ringe (Professor of Biochemistry and Chemistry, Brandeis University)Publisher: Oxford University Press Imprint: Oxford University Press Dimensions: Width: 22.10cm , Height: 1.20cm , Length: 27.90cm Weight: 0.584kg ISBN: 9780199556847ISBN 10: 0199556849 Pages: 224 Publication Date: 29 May 2008 Audience: Adult education , Further / Higher Education Format: Paperback Publisher's Status: Active Availability: To order Stock availability from the supplier is unknown. We will order it for you and ship this item to you once it is received by us. Table of Contents1: From Sequence to Structure 2: From Structure to Function 3: Control of Protein Function 4: From Sequence to Function: Case Studies in Structural and Functional Genomics 5: Structure DeterminationReviewsIt is well-written, makes for interesting reading and contains a number of excellent examples. The whole book appears to be an important, useful and timely one. * Roman Laskowski, European Bioinformatics Institute * This treatment and focus is much needed. It will be essential reading by students and faculty alike, and will serve as a crucial reference book for everyone in the biosciences. * James Spudich, Stanford University School of Medicine * A really good book provides a wealth of information in a manner that the reader remembers what he/she has read. This book does just that. The contents just pop into mind from time to time. This book will be a winner. * Tom Bruice, University of California, Santa Barbara * `A really good book provides a wealth of information in a manner that the reader remembers what he/she has read. This book does just that. The contents just pop into mind from time to time. This book will be a winner.' Tom Bruice, University of California, Santa Barbara `This treatment and focus is much needed. It will be essential reading by students and faculty alike, and will serve as a crucial reference book for everyone in the biosciences.' James Spudich, Stanford University School of Medicine `It is well-written, makes for interesting reading and contains a number of excellent examples. The whole book appears to be an important, useful and timely one.' Roman Laskowski, European Bioinformatics Institute `A really good book provides a wealth of information in a manner that the reader remembers what he/she has read. This book does just that. The contents just pop into mind from time to time. This book will be a winner.' Tom Bruice, University of California, Santa Barbara `This treatment and focus is much needed. It will be essential reading by students and faculty alike, and will serve as a crucial reference book for everyone in the biosciences.' James Spudich, Stanford University School of Medicine `It is well-written, makes for interesting reading and contains a number of excellent examples. The whole book appears to be an important, useful and timely one.' Roman Laskowski, European Bioinformatics Institute A really good book provides a wealth of information in a manner that the reader remembers what he/she has read. This book does just that. The contents just pop into mind from time to time. This book will be a winner. Tom Bruice, University of California, Santa Barbara This treatment and focus is much needed. It will be essential reading by students and faculty alike, and will serve as a crucial reference book for everyone in the biosciences. James Spudich, Stanford University School of Medicine It is well-written, makes for interesting reading and contains a number of excellent examples. The whole book appears to be an important, useful and timely one. Roman Laskowski, European Bioinformatics Institute Author InformationGregory A Petsko studied chemistry and classics as an undergraduate at Princeton University before going to Oxford as a Rhodes scholar to work for his PhD with David Phillips. He then pursued his interest in the mechanism of enzyme catalysis at the Massachusetts Institute of Technology where he taught courses in chemistry and detective fiction, before moving to Brandeis where he is currently Director of the Rosenstiel Center and has extended his research interests to include the use of yeast genetics to study the unfolded protein response pathway, and the mechanism of action of the ABC transporter proteins. Dagmar Ringe graduated in chemistry from Barnard College, Columbia, and took her PhD in bioorganic chemistry from Boston University. She then pursued her research interest in the study of enzyme catalysis by X-ray crystallography at the Massachusetts Institute of Technology before moving to Brandeis where she is Professor of Biochemistry and Chemistry and where the principal focus of her research is on structure-function relationships in enzymes of particular industrial and pharmaceutical importance. Tab Content 6Author Website:Countries AvailableAll regions |