Protein-protein Complexes: Analysis, Modeling And Drug Design

Author:   Martin Zacharias (Technische Univ Munchen, Germany)
Publisher:   Imperial College Press
ISBN:  

9781848163393


Pages:   400
Publication Date:   10 May 2010
Format:   Paperback
Availability:   In Print   Availability explained
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Protein-protein Complexes: Analysis, Modeling And Drug Design


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Author:   Martin Zacharias (Technische Univ Munchen, Germany)
Publisher:   Imperial College Press
Imprint:   Imperial College Press
Dimensions:   Width: 15.20cm , Height: 1.80cm , Length: 22.60cm
Weight:   0.612kg
ISBN:  

9781848163393


ISBN 10:   1848163398
Pages:   400
Publication Date:   10 May 2010
Audience:   College/higher education ,  Professional and scholarly ,  Tertiary & Higher Education ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   In Print   Availability explained
This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us.

Table of Contents

Introduction to Protein-Protein Interactions: Protein-Protein Complex Determination by X-ray Crystallography and Interface Analysis of Known Structures (J Janin); Protein-Protein Complex Determination and Analysis of Interactions Using NMR Spectroscopy (J Werner); Perspective on Protein-Protein Interactions in Macromolecular Assemblies (R Bahadur); Energetics of Protein-Protein Interactions (I Jelezarov); Kinetics of Complex Formation: Theory and Experiment (R Wade); Prediction of Putative Protein Interaction Regions and Interaction Geometries: Prediction of Protein Interaction Regions Based on Evolutionary Information (O Lichtarge); Prediction of Interaction Regions and Scoring Optimization (M Zacharias); Protein-Protein Docking Methods: A General Overview (C Prevost); Refinement of Docking Solutions (C Camacho); High-Resolution Docking Including Conformational Flexibility (O Furman); Experimental Constraint-Driven Docking (A Bonvin); Design and Targeting of Protein-Protein Interactions by Drugs and Protein Mimetics: Protein-Protein Interaction Modules of Medical Importance (H Sticht); Prediction/Calculation of Protein-Protein Binding Affinities and Mutation Effects (Fiorucci et al.); Design of Protein Mimetics That Interfere with Protein-Protein Interactions (K Mayo); Identifying Molecules to Inhibit Protein-Protein Interactions (T Berg); Combining Bioinformatics and Experiment to Design Inhibitors of Protein-Protein Interactions (G Colombo).

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