Protein Modifications in Pathogenic Dysregulation of Signaling

Author:   Jun-ichiro Inoue ,  Mutsuhiro Takekawa
Publisher:   Springer Verlag, Japan
Edition:   Softcover reprint of the original 1st ed. 2015
ISBN:  

9784431562535


Pages:   348
Publication Date:   23 October 2016
Format:   Paperback
Availability:   Manufactured on demand   Availability explained
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Protein Modifications in Pathogenic Dysregulation of Signaling


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Author:   Jun-ichiro Inoue ,  Mutsuhiro Takekawa
Publisher:   Springer Verlag, Japan
Imprint:   Springer Verlag, Japan
Edition:   Softcover reprint of the original 1st ed. 2015
Weight:   0.742kg
ISBN:  

9784431562535


ISBN 10:   4431562532
Pages:   348
Publication Date:   23 October 2016
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand   Availability explained
We will order this item for you from a manufactured on demand supplier.

Table of Contents

Preface.- Part I Novel Analytical Procedures for Signal Transduction.- 1 Phosphoproteomics-based Network Analysis of Cancer Cell Signaling Systems (Hiroko Kozuka-Hata and Masaaki Oyama).- 2 Phos-tag-based Affinity Chromatography Techniques for Enrichment of the Phosphoproteome (Eiji Kinoshita, Emiko Kinoshita-Kikuta, and Tohru Koike).- 3 Visualization of Intracellular Signaling with Fluorescence Resonance Energy Transfer-based Biosensors (Kazuhiro Aoki).- 4 Technology of Wheat Cell-free Based Protein Array for Biochemical Analyses of Protein Kinases and Ubiquitin E3 Ligases (Hirotaka Takahashi, Keiichirou Nemoto, Ramadan Abdelaziz, Atsushi Uematsu, and Tatsuya Sawasaki).- Part II Mathematical Simulation of Signal Transduction.- 5 Potential Roles of Spatial Parameters in the Regulation of NF-κB Oscillations, as Revealed by Computer Simulations (Daisuke Ohshima, Jun-ichiro Inoue, and Kazuhisa Ichikawa).- 6 Stochastic Simulation of Stress Granules (Daisuke Ohshima, KyokoArimoto-Matsuzaki, Taichiro Tomida, Mutsuhiro Takekawa, and Kazuhisa Ichikawa).- 7 Temporal Coding of Insulin Signaling (Hiroyuki Kubota and Shinya Kuroda).- Part III Structural Analysis of Signal Transduction.- 8 Structural Biology of Protein Post-transcriptional Modifications and Cellular Signaling (Kazuki Kato, Hiroshi Nishimasu, Ryohei Ishii, Osamu Nureki, and Ryuichiro Ishitani).- 9 Structural Basis for the Signal Initiation by TNF and TNFR (Teruya Nakamura, Yohei Mukai, Yasuo Tsutsumi, and Yuriko Yamagata).- 10 Regulation of NF-κB Pathway by Linkage-specific Ubiquitin-binding Domains (Yusuke Sato).- Part IV Regulation of Signal Transduction by Post-translational Modifications and Its Pathogenic Dysregulation.- 11 NF-κB Signaling and Lymphoid Malignancies (Shoji Yamaoka).- 12 Ubiquitination-mediated NF-κB Regulation in Inflammatory Response (Fuminori Tokunaga).- 13 NF-κB Signaling in Osteoclastogenesis (Yuu Taguchi, Jin Gohda, and Jun-ichiro Inoue).- 14 Mitogen-activated Protein Kinase Signaling and Cancer (Mutsuhiro Takekawa and Yuji Kubota).- 15 Critical Roles of the AKT Substrate Girdin in Disease Initiation and Progression (Atsushi Enomoto, Liang Weng, and Masahide Takahashi).- 16 Protein Modifications Pace the Circadian Oscillation of Biological Clocks (Hikari Yoshitane and Yoshitaka Fukada).- 17 Keap1-Nrf2 Regulatory System and Cancer (Keiko Taguchi and Masayuki Yamamoto).- 18 Actin Filament Formation in Myofibrils and Cell Protrusions Regulated by Signal Transduction (Takeshi Endo and Kazunori Takano).- 19 Molecular Signaling and its Pathogenic Alterations in Neuromuscular Junction Formation and Maintenance (Ryo Ueta and Yuji Yamanashi).- 20 Post-translational Modification of Tcf/Lef: New Insights into the Regulation of Wnt/β-catenin Signaling (Tohru Ishitani).- BM Index.

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