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OverviewFull Product DetailsAuthor: Silvia Maria Doglia , Marina LottiPublisher: John Wiley & Sons Inc Imprint: John Wiley & Sons Inc Dimensions: Width: 16.30cm , Height: 2.00cm , Length: 24.40cm Weight: 0.567kg ISBN: 9781118448526ISBN 10: 1118448529 Pages: 288 Publication Date: 08 August 2014 Audience: Professional and scholarly , Professional & Vocational Replaced By: 9781118470442 Format: Hardback Publisher's Status: Active Availability: Out of stock  The supplier is temporarily out of stock of this item. It will be ordered for you on backorder and shipped when it becomes available. Table of ContentsContributors vii Preface xi Introduction to the Wiley Series in Protein and Peptide Science xiii 1 Fundamentals of Protein Folding 1 Vladimir N. Uversky 2 Recruiting Unfolding Chaperones to Solubilize Misfolded Recombinant Proteins 63 Rayees U.H. Mattoo and Pierre Goloubinoff 3 Osmolytes as Chemical Chaperones to Use in Protein Biotechnology 77 Ario de Marco 4 Inclusion Bodies in the Study of Amyloid Aggregation 93 Anna Villar-Piqué and Salvador Ventura 5 Protein Aggregation in Unicellular Eukaryotes 117 Marina Caldara, Joris Winderickx, and Vanessa Franssens 6 Structural Properties of Bacterial Inclusion Bodies 151 Antonino Natalello, Diletta Ami, and Silvia Maria Doglia 7 Residue-Specific Structural Studies of Inclusion Bodies 181 Christian Wasmer, Marielle Wälti, Yongli Chen, and Lei Wang 8 Biomedical Applications of Bacterial Inclusion Bodies 203 Imma Ratera, Spela Peternel, Joaquin Seras-Franzoso, Olivia Cano-Garrido, Elena García-Fruitós, Rafael Cubarsí, Esther Vazquez, José Luis Corchero, Escarlata Rodríguez-Carmona, Jaume Veciana, and Antonio Villaverde 9 Aggregation of Recombinant Proteins: Understanding Basic Issues to Overcome Production Bottlenecks 221 Marina Lotti and Loredano Pollegioni 10 Fusion to a Pull-Down Module: Designing Enzymes to Form Biocatalytically Active Insoluble Aggregates 247 Bernd Nidetzky Index 263ReviewsAuthor InformationSILVIA MARIA DOGLIA, PhD, is Professor of Physics at the University of Milano-Bicocca, Italy. She received her Laurea degree in Physics at the University of Milano. She has been Staff Research Scientist of the Italian National Research Council; Visiting Scientist at the University of Stockholm; Visiting Professor at the Universities of Orléans (Fr) and of Reims (Fr). Her research in Biophysics at the University of Milano-Bicocca is focused on the study of protein folding and aggregation in vitro and in situ. MARINA LOTTI, PhD, is Professor of Biochemistry at the University of Milano-Bicocca, Italy, where she leads the group Protein Engineering and Industrial Enzymology, and is the Head of the Department of Biotechnology and Biosciences. She obtained her PhD degree at the Max-Planck Institute of Molecular Genetics, Berlin, and was a researcher of the Italian National Research Council. Major research topics include the production of recombinant proteins, protein aggregation, cold-active enzymes, and intrinsically disordered proteins. Tab Content 6Author Website:Countries AvailableAll regions |
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