Programmed Aging: Altersgene Und Ihre Funktion

Author:   Jana Doppeler ,  Roland Prinzinger
Publisher:   Franz Steiner Verlag Wiesbaden GmbH
Volume:   46.4
ISBN:  

9783515093002


Pages:   95
Publication Date:   01 October 2009
Format:   Paperback
Availability:   Out of stock   Availability explained
The supplier is temporarily out of stock of this item. It will be ordered for you on backorder and shipped when it becomes available.

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Programmed Aging: Altersgene Und Ihre Funktion


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English summary: Performance-reducing signs of aging and age-related diseases that are associated most frequently with the human aging process, such as Osteoporosis, arthritis and osteoarthritis, rheumatism, and Alzheimer's and Parkinson's disease, are absent in many organisms that die without visible and/or long-term signs of aging, often closely following a successful reproduction process. All this raises the obligatory (modern) question of genetic fixation of age (program theory of aging), as well as the question of the programmed death, which would then be enshrined within the genes. However, a singular, ultimate aging gene does not seem to exist. It is estimated that about 7,000 different regulator genes exist that affect aging directly or indirectly. To address them all makes little sense. In the present work, we represent the set of key genes known to be related to aging and describe the role they (could) play in the aging and life-limiting process. German and English text. German description: Die mit dem Alternsprozess des Menschen meist zusammenhangenden, die Leistung reduzierenden Alterns-Erscheinungen und Alterskrankheiten, wie z.aB. Osteoporose, Arthritis und Arthrose, Rheuma, Alzheimer und Parkinson, fehlen bei vielen Organismen, die oft eng korreliert nach einer erfolgreichen Fortpflanzung ohne auffallige und/oder lang andauernde Alterserscheinungen sterben. All dies wirft zwingend die (moderne) Frage nach einer genetischen Fixierung des Lebensalters auf (Programmtheorie des Alterns); es ist auch die Frage nach dem aprogrammierten Tod, der dann in den Genen verankert sein muesste. Ein singulares, ultimatives Altersgen scheint es aber nicht zu geben. Man schatzt, dass es ca. 7a000 verschiedene Regulator-Gene gibt, die das Altern direkt oder indirekt mitbestimmen. Sie alle darzustellen ist wenig sinnvoll. In der vorliegenden Arbeit stellen wir dar, welche wichtigen Alters-Gene bekannt sind und welche Rolle diese im Hinblick auf den Alternsprozess und die Lebensbegrenzung spielen (konnten).

Full Product Details

Author:   Jana Doppeler ,  Roland Prinzinger
Publisher:   Franz Steiner Verlag Wiesbaden GmbH
Imprint:   Franz Steiner Verlag Wiesbaden GmbH
Volume:   46.4
Weight:   0.222kg
ISBN:  

9783515093002


ISBN 10:   3515093001
Pages:   95
Publication Date:   01 October 2009
Audience:   General/trade ,  General
Format:   Paperback
Publisher's Status:   Active
Availability:   Out of stock   Availability explained
The supplier is temporarily out of stock of this item. It will be ordered for you on backorder and shipped when it becomes available.
Language:   German

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