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OverviewThe complement system is an evolutionary ancient mechanism that plays an essential role in innate immunity and contributes to the acquired immune response. It is a versatile first line of defense of hosts against various pathogens. Three modes of activation, known as classical, alternative and lectin pathway, lead to the initiation of a common terminal lytic pathway. The terminal complement components (TCCs: C6, C7, oA, oB, and C9) are encoded by the genes C6, C7, oA, oB, oG, and C9. Herein the author describes the characterization of the porcine genes in terms of sequence and sequence variation obtained in different breeds, homology to other species, chromosomal position and genetic mapping as well as the effect of genetic variation on the hemolytic complement activity. The results promote the porcine genes encoding terminal complement components as candidate genes for improvement of disease resistance and animal health. Full Product DetailsAuthor: Do Vo Anh KhoaPublisher: VDM Verlag Imprint: VDM Verlag Dimensions: Width: 22.90cm , Height: 1.20cm , Length: 15.20cm Weight: 0.304kg ISBN: 9783836494014ISBN 10: 3836494019 Pages: 204 Publication Date: 02 May 2010 Audience: General/trade , General Format: Paperback Publisher's Status: Active Availability: In Print  This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us. Table of ContentsReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |
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