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OverviewType 1 diabetes (T1DM) is an autoimmune disease characterized by immune destruction of insulin-producing pancreatic β cells. This leads to dysfunctional regulation of blood glucose levels in T1DM patients. The destruction of β -cells of Langerhans islets is caused by infiltration of dendritic cells, macrophages and T lymphocytes. Normally, genetic susceptibility (association) studies depend on assessing the role of genotype markers (typically SNPs) in the susceptibility to the disease of interest in a case- control or family based sample. Many genes associated with type 1 diabetes mellitus, CTLA-4, PTPN22, IL-10, IL-18, VIT-D receptor are one of the common confirmed T1DM susceptibility genes Full Product DetailsAuthor: Al-Shehmany Ali SalimPublisher: LAP Lambert Academic Publishing Imprint: LAP Lambert Academic Publishing Dimensions: Width: 15.20cm , Height: 0.40cm , Length: 22.90cm Weight: 0.118kg ISBN: 9783659756375ISBN 10: 3659756377 Pages: 72 Publication Date: 10 July 2015 Audience: General/trade , General Format: Paperback Publisher's Status: Active Availability: In stock  We have confirmation that this item is in stock with the supplier. It will be ordered in for you and dispatched immediately. Table of ContentsReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |
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