Overview

This book explores a new challenge in virology: to understand how physical properties of virus particles (virions) and viruses (infected cells) affect the course of an infection. Insights from the emerging field of physical virology will contribute to understanding of the physical nature of viruses and cells, and will open new ways for anti-viral interference. Nine chapters and an editorial written by physicists, chemists, biologists and computational experts describe how virions serve as trail blazers in uncharted territory of cells. The authors outline how particles change in composition as they interact with host cells. Such virus dynamics are crucial for virus entry into cells and infection. It influences the modern concepts of virus-host interactions, viral lineages and evolution. The volume gives numerous up-to-date examples of modern virology and provides a fascinating read for researchers, clinicians and students in the field of infectious diseases.

Full Product Details

Author:   Urs F. Greber
Publisher:   Springer Nature Switzerland AG
Imprint:   Springer Nature Switzerland AG
Edition:   1st ed. 2019
Volume:   1215
Weight:   0.454kg
ISBN:  

9783030147433

ISBN 10:   3030147436
Pages:   235
Publication Date:   14 August 2020
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.

Table of Contents

Editorial: Physical Virology and the Nature of Virus Infections.- Single Virion Tracking Microscopy for the Study of Virus Entry Processes in Live Cells and Biomimetic Platforms.- Structural Insights into Rotavirus Entry.- The HIV-1 Capsid: More than Just a Delivery Package.- Membrane-Containing Icosahedral Bacteriophage PRD1: The Dawn of Viral Lineages.- Structure and Function of Negri Bodies.- Virus Maturation.- Atomic Force Microscopy of Viruses.- Alkalinization of Icosahedral Non-enveloped Viral Capsid Interior Through Proton Channeling.- Computational Virology: Molecular Simulations of Virus Dynamics and Interactions.

Reviews

The intended audience is researchers, clinicians, and students in the field of infectious diseases. In addition, pathologists and virologists will find the book extremely useful. ... Given that a better understanding of the physical nature of virions and infected cells will open new ways for antiviral interference, this book will surely appeal to the intended audience. (Omer Iqbal, Doody's Book Reviews, March 27, 2020)

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