Overview

Phosphonate Chemistry, Technology, and Applications: Synthesis, Chemistry, and Biomedical Applications gathers important up-to-date information on several modern topics, including the synthetic aspects and chemical transformations of phosphonic acids and their metal derivatives, metal phosphonate hybrid materials, optical properties of metal phosphonates, phosphonate-based systems for calcium-related disorders, metal-bisphosphonates as controlled release systems, biology of phosphonates and a plethora of biomedical applications. This comprehensive volume is the first part of a 2-volume set. It covers extensively the latest developments in phosphonate chemistry and includes crucial bibliographic information. It explores the constantly expanding world of organic phosphonate compounds and metal phosphonate networks, beyond conventional boundaries. This exploration includes diverse applications derived from these compounds, enhancing the reader's grasp of this dynamic and evolving field.

Full Product Details

Author:   Konstantinos D. Demadis (Professor, Department of Chemistry, University of Crete, Heraklion, Greece)
Publisher:   Elsevier - Health Sciences Division
Imprint:   Elsevier - Health Sciences Division
Weight:   0.450kg
ISBN:  

9780443333743

ISBN 10:   0443333742
Pages:   546
Publication Date:   28 November 2025
Audience:   Professional and scholarly ,  College/higher education ,  Professional & Vocational ,  Postgraduate, Research & Scholarly
Format:   Paperback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

Part I: The organic synthetic chemistry of phosphonic acids and phosphonates I.1. Synthesis of phosphonate-based scale inhibitors for oilfield scale management. Mohamed Mady (Qatar University, Qatar) I.2. Synthesis of heterocyclic phosphonic acids. Elpiniki Chachlaki and Konstantinos D. Demadis (University of Crete, Greece) I.3. Synthesis of (poly)phosphonic acids: An industrial Perspective. Stephan Liebsch (Zschimmer & Schwarz Mohsdorf, Germany) I.4. Synthesis of phosphonates for pharmaceutical applications. György Keglevich (Budapest University of Technology and Economics, Hungary) I.5. Fluorescent phosphonates for water treatment applications. Konstantin Popov (JSC “Fine Chemicals R&D Centre”, Russian Federation) I.6. Efficient syntheses of N-heterocylic, homocyclic and aliphatic dronic acids (Nader Noroozi Pesyan, Urmia University, Iran) I.7. Phosphonate and phosphinate chelators for imaging applications. Petr Hermann (Charles University, Czech Republic) I.8. Phosphonate-based conjugates. Petri Turhanen (University of Eastern Finland, Finland) Part II. Synthetic, structural and computational chemistry of phosphonates and metal phosphonates II.1. Metal phosphonate materials containing co-ligands. Jiri Pinkas (Masaryk University, Czech Republic) II.2. Structural chemistry of metal-triphosphonate materials. Feodor Chausov (Ural Branch of Russian Academy of Sciences, Russian Federation) II.3. Metal-phosphonate-derived electrocatalysts. Rosario Colodrero (University of Malaga) II.4. Metal phosphonates as supports for gold nanoparticles. Monica Pica (University of Perugia, Italy) II.5. Porous and functional metal phosphonate frameworks. Tao Zheng (Northwestern Polytechnical University, China) II.6. Functional metal phosphonates from rigid phosphonic acids. Jean-Michel Rueff (École Nationale Supérieure d' Ingénieurs de Caen, France) II.7. Mechanochemical synthesis of metal phosphonates. Franziska Emmerling (Bundesanstalt für Materialforschung und -prüfung, Germany) II.8. Polyoxometallates with Phosphonate Linkers. Xikui Fang (Harbin Institute of Technology, China) II.9. Lanthanide phosphonate chemistry and applications. Filipe Almeida Paz (University of Aveiro) II.10. Alkaline-earth metal phosphonate chemistry. Antonia Neels (Swiss Federal Laboratories for Materials Science and Technology, Switzerland) II.11. QSAR studies and molecular docking of phosphonates as COVID-19 inhibitors. Khodayar Gholivand (Tarbiat Modares University, Iran) Part III. Phosphonate-based materials for medicinal, pharmaceutical, and related applications III.1. Alendronate-decorated strontium-containing bioactive glass nanoparticles with dual osteogenic and anti-osteoclastic effects for osteoporosis. Zhaoying Wu (Sun Yat-sen University, China) III.2. Clodronate: an anti-osteolytic drug. Eugene McCloskey (University of Sheffield, United Kingdom) III.3. Phosphonic acids in biology and biochemistry. Pawel Kafarski (Wroclaw University of Science and Technology, Poland) III.4. Stimuli-responsive metal phosphonates. Norbert Stock (Christian-Albrechts-University, Germany) III.5. Metal phosphonate frameworks as optical sensors. Flávio Figueira (University of Aveiro, Portugal) III.6. Metal phosphonates for photodynamic applications. Kaplan Kiracki (Czech Academy of Sciences, Czech Republic) III.7. Metal phosphonates with antibacterial properties. Riccardo Vivani (University of Perugia, Italy) III.8. The contribution of phosphonate chemistry to PET and related techniques. Clara Vinas Teixidor (Universiat Autònoma de Barcelona, Spain) III.9. Health promoting strategies based on phosphonates. Susana Braga (University of Aveiro, Portugal) III.10. The chemistry and biology of anti-osteolytic phosphonates and metal phosphonates. Vilmalí López-Mejías (University of Puerto Rico, Puerto Rico) III.11. Amphiphilic phosphonates for cell transfection. Paul-Alain Jaffrès (University of Brest, France) III.12. Biologically coupled bisphosphonate chaperones. Charles E. McKenna (University of Southern California, USA) III.13. Synthesis and Anticancer Activity of Phosphinoylated and Phosphonoylated Heterocycles. Konstantin Karaghiosoff (Ludwig-Maximilians-University, Germany) III.14. Phosphonate Natural Products and their Biosynthetic Pathways. William W. Metcalf (University of Illinois, USA) III.15. Phosphonates as antiviral agents. Erik De Clercq (KU Leuven, Belgium) Part IV. Phosphonates for industrial and environmental applications IV.1. Scale and deposit dissolution mediated by phosphonic acids. Chen Wu (Harbin University of Science and Technology, China) IV.2. The role of phosphonate chemistry in engine coolant applications. Georgia Skordalou and Konstantinos D. Demadis (University of Crete, Greece) IV.3. Phosphonate-based scale inhibitors in geothermal applications. Michaela Kamaratou and Konstantinos D. Demadis (University of Crete, Greece) IV.4. Metal phosphonates in electrochemical oxidation degradation applications. Nicoleta Plesu (Institute of Chemistry, Romanian Academy, Romania) IV.5. Green Alternative Approaches to the Synthesis of Metal Organic Frameworks. Aurelia Visa (Institute of Chemistry, Romanian Academy, Romania) IV.6. Phosphonates as kinetic hydrate inhibitors for oilfield applications. Malcolm Kelland (University of Stavanger, Norway) IV.7. Metal phosphonates for separation applications. Sheng Hu (China Academy of Engineering Physics, China) IV.8. Metal phosphonates for CO2 capture and fixation. Marco Taddei (University of Pisa, Italy) IV.9. Porous metal phosphonates catalysts for biorefinery applications. Wouter Marchal (Hassel University, Belgium) IV.10. Phosphonic acid inhibitors for oilfield scale. Ping Zhang (University Macau, China) IV.11. Metal phosphonates for organic transformations. Joao Rocha (University of Aveiro, Portugal) IV.12. Glyphosate exposure and toxicology. Stephen O. Duke (University of Mississippi, USA) IV.13. The Environmental Fate of Natural and Anthropogenic Phosphonates. Alessio Peracchi (University of Parma, Italy) Part V. Metal phosphonate materials for energy, magnetic, optical, and catalytic applications V.1. Metal phosphonate coordination polymers as supercapacitors. Qi Liu (Changzhou University, China) V.2. Metal phosphonates in catalysis. Ritambhara Jangir (Sardar Vallabhbhai National Institute of Technology, India) V.3. Proton conducting metal phosphonates. George Shimizu (University of Calgary, Canada) V.4. Proton conductivity of zirconium phosphates and phosphonates. Anna Donnadio (University of Perugia, Italy) V.5. Metal phosphonates as supports for nanoparticles and relevant applications. Morena Nocchetti (University of Perugia, Italy) V.6. Electrocatalytic properties of phosphonate-derived materials (University of Malaga, Spain) V.7. Conducting metal phosphonates. Gündoğ Yücesan (University of Dusseldorf, Germany) V.8. Materials based on phosphonate esters. Ramaswamy Murugavel (Indian Institute of Technology, India) V.9. Chiral metal phosphonates. Li-Min Zheng (Nanjing University, China) V.10. Synthesis and catalytic performance of mesoporous metal phosphonates. Vera Meynen (University of Antwerp, Belgium) V.11. Metal phosphonates for water splitting. Patricia Horcajada (IMDEA Energy, Spain)

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Author Information

Kostas Demadis is a Professor of Chemistry at the Department of Chemistry, University of Crete, Greece. He is head of the Crystal Engineering, Growth & Design Laboratory delving into diverse fields of chemistry and chemical technology. His research group is involved in projects that embrace phosphonate and metal phosphonate chemistry (synthesis, characterization and applications of metal phosphonate materials), functional hybrid materials, silicon chemistry (modeling of biosilicification mechanisms), water treatment issues (mineral scale inhibition, corrosion control, metal ion absorption), controlled release of active pharmaceutical ingredients (in particular phosphonate-based drugs), and green chemistry and engineering. Professor Demadis has published over 220 papers in peer reviewed journals, 24 chapters in books, 8 books, and is the inventor of 2 patents.

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