Phosphoinositides in Subcellular Targeting and Enzyme Activation

Author:   Harald Stenmark
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Edition:   2004 ed.
Volume:   282
ISBN:  

9783540009504


Pages:   209
Publication Date:   15 September 2003
Format:   Hardback
Availability:   Out of stock   Availability explained
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Phosphoinositides in Subcellular Targeting and Enzyme Activation


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Overview

Cells of the immune system are activated by a variety of stimuli that are derived from other cells, ingested material or from invading microorganisms. This issue of CTMI focuses on the mechanisms of phosphoinositide-mediated protein recruitment to intracellular membranes.

Full Product Details

Author:   Harald Stenmark
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Imprint:   Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Edition:   2004 ed.
Volume:   282
Dimensions:   Width: 15.50cm , Height: 1.50cm , Length: 23.50cm
Weight:   0.611kg
ISBN:  

9783540009504


ISBN 10:   3540009507
Pages:   209
Publication Date:   15 September 2003
Audience:   General/trade ,  General
Format:   Hardback
Publisher's Status:   Active
Availability:   Out of stock   Availability explained
The supplier is temporarily out of stock of this item. It will be ordered for you on backorder and shipped when it becomes available.

Table of Contents

List of Contents.- Phosphoinositide Involvement in Phagocytosis and Phagosome Maturation.- Regulation of Endocytosis by Phosphatidylinositol 4,5-Biphosphate and ENTH Proteins.- Membrane Targeting by Pleckstrin Homology Domains.- Protein Targeting to Endosomes and Phagosomes via FYVE and PX Domains.- Regulation of the Actin Cytoskeleton by PI(4,5)P2 and PI(3,4,5)P3.- Roles of PI3K in Neutrophil Function.- Nuclear Phosphoinositides and Their Functions.

Reviews

From the reviews: <p> The book consists of seven chapters that focus on the various functions of PtdIns. a ] summarises recent advances in the burgeoning field of inositol lipids and provides a snapshot of where the field stands in 2003. The field is moving rapidly but this volume will be a useful addition for many researchers who have only recently discovered that their favourite protein is regulated by PtdIns. (Shamshad Cockcroft, nature cell biology, Vol. 6 (6), June, 2004)


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