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Author:   Larry L. Augsburger (University of Maryland, Baltimore, USA) ,  Stephen W. Hoag (University of Maryland University of Maryland University of Maryland, Baltimore, MD, USA University of Maryland, Baltimore, USA)
Publisher:   Taylor & Francis Inc
Imprint:   CRC Press Inc
Edition:   3rd edition
Dimensions:   Width: 17.80cm , Height: 10.20cm , Length: 25.40cm
Weight:   3.333kg
ISBN:  

9781420063455

ISBN 10:   1420063456
Pages:   1552
Publication Date:   03 June 2008
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Mixed media product
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

Volume I: Fundamentals and Unit Operations Principles of Sampling for Particulate Solids. Particle Size and Shape. Flow: General Principles of Bulk Solids Handling. Blending and Blend Uniformity. Milling. Drying. Spray Drying: Theory and Pharmaceutical Applications. Wet Granulation. Dry Granulation. The Preparation of Pellets by Extrusion/Spheronization. Coating Processes and Equipment. Aqueous Polymeric Film Coating. The Application of Thermal Analysis to Pharmaceutical Dosage Forms. Preformulation Studies for Tablet Formulation Development. Stability Kinetics. Compaction Simulation. Compression and Compaction. Volume II: Rational Design and Formulation with Excipients Preface. Mass Transfer (from solid oral dosage forms). Approaches for Improving Bioavailability of Poorly Soluble Drugs. Experimental Design and Multivariate Optimization Tools in Formulation and Process Development. Knowledge-Based Systems and Other AI Applications for Tableting. Direct Compression and the Role of Filler-Binders. Disintegrants in Tableting. Orally Disintegrating Tablets and Related Tablet Formulations. Formulation Challenges: Multiple Vitamin and Mineral Dosage Forms. Botanicals and Their Formulation into Oral Solid Dosage Forms. Formulation of Specialty Tablets for Slow Oral Dissolution. Formulation of Specialty Tablets for Slow Oral Dissolution. Swellable and Rigid Matrices Controlled Release Matrices with Cellulose Ethers. Carragenenans in Solid Dosage Form Design. Osmotic Systems. Tableting of Multiparticulate Modified Release Systems. Volume III: Modern Manufacture and Control Preface. Tooling for Pharmaceutical Processing. Tablet Press Instrumentation in the Research and Development Environment. Pharmaceutical Manufacturing: Changes in Paradigms. A Forward-Looking Approach to Process Scale-Up for Solid Dose Manufacturing. Dissolution and Drug Release. Setting Dissolution Specifications. Mechanical Strength of Tablets. CGMPs for the 21st Century and ICH Quality Initiatives. Intellectual Property, Patent and Patenting Process in Pharmaceutical Industry. Near-Infrared Chemical Imaging of Pharmaceutical Oral Solid Dosage Forms. Surface Area, Porosity and Related Physical Characteristics.

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Larry L. Augsburger, Stephen W. Hoag

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