Overview

This new research level book examines how host and pathogen have co-evolved to reach the current balance of power; and investigates if persistent colonization or infection is a biological accident or the result of an evolved equilibrium. The authors discuss the differences between acute bacterial infections and infections that persist for months or years as well as the fundamental differences among acute but self-limiting bacterial infections, parasitism, and commensal states that may not be pathogenic. The book covers clinical syndromes and applications as well as providing a thorough grounding in the basic science.

Full Product Details

Author:   James P Nataro ,  Martin J Blaser ,  Susanna Cunningham-Rundles
Publisher:   American Society for Microbiology
Imprint:   American Society for Microbiology
Dimensions:   Width: 17.50cm , Height: 2.90cm , Length: 25.00cm
Weight:   1.080kg
ISBN:  

9781555811594

ISBN 10:   1555811590
Pages:   453
Publication Date:   12 May 2000
Audience:   College/higher education ,  Professional and scholarly ,  Undergraduate ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Out of stock  
The supplier is temporarily out of stock of this item. It will be ordered for you on backorder and shipped when it becomes available.

Table of Contents

I. Introduction II. The Biology of Persistent Infection Microbial Mechanisms for Establishing Persistence - Antigenic Variation Microbial Mechanisms for Establishing Persistence - Privileged Intracellular Sites Microbial Mechanisms for Establishing Persistence - Avoidance of the Immune Response Mathematical Modeling of Persistent Infections The Natural History and Ecology of Commensal Human Flora Pathological Consequences of Commensalism Bacterial Infections in the Immunocompromised Host Immunologic Basis of Persistent Bacterial Infections III. Persistent Bacterial Pathogens Neisseria gonorrheae Chlamydia spp. Helicobacter pylori Borrelia spp. Pseudomonas aeruginose Infection in Cystic Fibrosis Patients Mycobacterial Infections Bartonella spp. Treponema pallidum IV. Pathogenesis of Persistent Clinical Syndromes Endocarditis Osteomyelitis/Septic Arthritis Abscesses Dental Plaque Biofilms and Device Infections

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