Overview

Written and edited by global leaders in the field, Pediatric Liver Transplantation: A Clinical Guide covers all aspects of treatment and management regarding this multifaceted procedure and unique patient population. This practical reference offers detailed, focused guidance in a highly templated, easy-to-consult format, covering everything from pre-transplantation preparation to surgical techniques to post-operative complications. Provides an in-depth understanding of all aspects of pediatric liver transplantation, ideal for pediatric hepatologists, pediatric transplant surgeons, and others on the pediatric transplant team. Covers all surgical techniques in detail, including split graft, living related, auxiliary, and domino. Discusses pediatric liver transplantation consideration for an increasing number of additional metabolic, hematologic and renal conditions; breakthroughs in grafting and stem cell therapy; and techniques and present role of hepatocyte transplantation. Uses a quick-reference templated format; each chapter includes an overview, pathophysiology, conventional management, controversies, and bulleted summary of key take-aways. Includes state-of-the-art mini-reviews based on updated references and author experience throughout the text. Features a full-color design with numerous algorithms, figures, and radiological and histopathological photos. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

Full Product Details

Author:   Nedim Hadzic ,  Ulrich Baumann (Consultant Paediatric Hepatologist) ,  Valérie MCLIN
Publisher:   Elsevier - Health Sciences Division
Imprint:   Elsevier - Health Sciences Division
Weight:   1.220kg
ISBN:  

9780323636711

ISBN 10:   0323636713
Pages:   512
Publication Date:   15 March 2021
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In stock  
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Table of Contents

Evolution of transplantation medicine BRIEF HISTORY OF PLT HEALTH SYSTEM BACKGROUND REQUIREMENTS FOR PLT Before transplantation Brain death criteria Non-heart beating donors Donor procurement Managing a scarce resource: Differences in donor allocation across the world INDICATIONS AND CONTRAINDICATIONS (and their evolution) - General aspects (List of diagnoses) PREPARATION FOR PLT Medical (immunisations/cardiac/renal/neurological aspects) Surgical and Radiological aspects Psychological/Social aspects Paediatric liver transplantation ANAESTHETIC ASPECTS (Risk assessment) SURGICAL ASPECTS (Choice of donor for PLT, Prevention of thrombosis/anticoagulation) SURGICAL TECHNIQUES Split graft Living-related Auxiliary Domino Techniques and present role of hepatocyte transplantation STRATEGIES IN IMMUNE SUPPRESSION (Immune ablation, renal-sparing, steroid-sparing) Management after Transplantation INTENSIVE CARE ASPECTS ANTI-INFECTION STRATEGIES Viral Bacterial Fungal EARLY COMPLICATIONS SURGICAL (biliary, vascular, etc.) MEDICAL ROLE OF HISTOLOGY AFTER PLT ROLE OF RADIOLOGY AND INTERVENTIONAL RADIOLOGY AFTER PLT LATE COMPLICATIONS SURGICAL (graft re-modelling, secondary portal hypertension/shunts) MEDICAL (recurrent disease post-PLT, de novo AIH, post-transplant lymphoproliferative disease, nephrotoxicity) PSYCHOSOCIAL ASPECTS AFTER PLT (social reintegration, medication adherence, family planning, education) PROSPECTS FOR IMMUNE TOLERANCE (possibilities for safe withdrawal of immunosuppression) TRANSITION TO ADULT SERVICES (smooth handover of care to a different system) FUTURE REQUIREMENTS

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