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OverviewThe Oxford Handbook of Nucleic Acid Structure is a comprehensive reference text on all aspects of nucleic acid sturcture. Particular emphasis is placed on the results from X-ray crystallography and NMR studies, with both methods being given equal weight. The nineteen chapters describe in detail the variety of DNA and RNA structural types discovered to date with all the major 'native' structures being represented. The text progresses systematically through the polymorphs of double helical DNA through to the higher-order organizations of triplexes, quadruplexes, and junctions, then to RNA structures in their various degrees of complexity. Each chapter has been written by authorities in the field who have worked together to provide this comprehensive text on nucleic acid structure. The whole project has been brought together and edited by Professor Stephen Neidle who is Director of the CRC Biomolecular Structure Unit at the Institute of Cancer Research. Full Product DetailsAuthor: Stephen Neidle (Professor, CRC Biomolecular Structure Unit, Institute of Cancer Research, University of London)Publisher: Oxford University Press Imprint: Oxford University Press Dimensions: Width: 17.20cm , Height: 4.20cm , Length: 24.70cm Weight: 1.457kg ISBN: 9780198500384ISBN 10: 0198500386 Pages: 680 Publication Date: 25 March 1999 Audience: Professional and scholarly , Professional & Vocational Format: Hardback Publisher's Status: Out of Print Availability: Out of stock Table of Contents1: [data missing] 2: Polynucleotide secondary structures: an historical perspective 3: Base and base pair morphologies, helical parameters, and definitions 4: The nucleic acid database: a research and teaching tool 5: Simulation of nucleic acid structure 6: A-DNA duplexes in the crystal 7: Helix structure and molecular recognition by B-DNA 8: The single-crystal structures of Z-DNA 9: Standard DNA duplexes and RNA-DNA hybrids in solution 10: Nucleic acid hydration 11: Single crystal X-ray diffraction studies on the non Watson-Crick base associations of mismatches, modified bases, and non-duplex oligonucleotide structures 12: DNA mismatches in solution 13: Structures on nucleic acid triplexes 14: [data missing] 15: DNA bending by adenine-thymine tracts 16: Structures and interactions of helical junctions in nucleic acids 17: DNA higher-order structures 18: Crystallographic structures of RNA oligoribonucleotides and ribozymes 19: RNA structure in solution 20: Transfer RNAReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |