Overview

This work addresses the origin and evolution of new gene functions. Although interest in evolutionary novelties can be traced back to the time of Darwin, the appreciation and systematical experimental pursuit of the origin and evolution of new gene functions did not appear until the early 1990s. Sixteen chapters from pioneers and leading scientists in this emerging field provide overviews of how new genes with novel functions originated and evolved. Broad issues related to new gene evolution are analyzed, ranging from molecular mechanisms to population genetics to theoretical conjecture of the minimum building blocks for protein diversity. Both insightful reviews and original results of theoretical and experimental analyses are presented, which should be valuable for researchers and students in further pursuit of the field of new gene evolution.

Full Product Details

Author:   Manyuan Long
Publisher:   Springer-Verlag New York Inc.
Imprint:   Springer-Verlag New York Inc.
Volume:   10
Dimensions:   Width: 21.00cm , Height: 1.40cm , Length: 27.90cm
Weight:   0.838kg
ISBN:  

9781402013966

ISBN 10:   1402013965
Pages:   199
Publication Date:   31 July 2003
Audience:   College/higher education ,  Professional and scholarly ,  Undergraduate ,  Postgraduate, Research & Scholarly
Format:   Hardback
Publisher's Status:   Active
Availability:   Out of stock  
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Table of Contents

The contribution of RNAs and retroposition to evolutionary novelties.- The emergence of a synthetic theory of intron evolution.- Introns in gene evolution.- Functional divergence in protein (family) sequence evolution.- The EBG system of E. coli: origin and evolution of a novel ß-galactosidase for the metabolism of lactose.- The fucosyltransferase gene family: an amazing summary of the underlying mechanisms of gene evolution.- Origin of new genes: evidence from experimental and computational analyses.- Transposable elements and vertebrate protein diversity.- Birth of ‘human-specific’ genes during primate evolution.- Evolution by gene duplication revisited: differentiation of regulatory elements versus proteins.- Modular assembly of genes and the evolution of new functions.- Origin and evolution of a new gene expressed in the Drosophila sperm axoneme.- Molecular mechanisms of exon shuffling: illegitimate recombination.- Recent evidence for the Exon Theory of Genes.- The universe of exons revisited.- Population-genetic models of the fates of duplicate genes.

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