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OverviewOncogenes and tumour suppressor genes have been the focus of much research because of their role not only in cancer but also in normal cell growth and differentiation. Oncogenes and Tumour Suppressors is a unique volume that brings together a team of leading researchers to present and critically assess our current knowledge. The book covers two major areas of interest: oncogenes and signal transduction, and tumour supressors and cell cycle control. Topics covered include the mechanisms of oncogene perturbation; growth factors and their receptors in cell transformation; oncogenic cytoplasmic protein tyrosine kinases; the RAS/RAP/ERK signal transduction pathway; oncogenic transcription factors; mammalian cell cycle control; the retinoblastoma gene product and its relatives; the tumour suppressor gene p53; tumour suppressors and the inheritance of cancer; the clinical relevance of oncogenes. Oncogenes and Tumour Suppressors is a major review work that provides an unparalleled summary of our current understanding of this field as viewed by some of its leading researchers. It is of interest to all those involved in research on the cell cycle, signal transduction, and cancer biology. The book is also an excellent reference source with over 1800 selected citations to the primary literature. Full Product DetailsAuthor: Gordon Peters , Karen H. VousdenPublisher: Oxford University Press Imprint: Oxford University Press Volume: 19 Dimensions: Width: 18.90cm , Height: 1.90cm , Length: 24.30cm Weight: 0.673kg ISBN: 9780199635948ISBN 10: 0199635943 Pages: 352 Publication Date: 24 July 1997 Audience: Professional and scholarly , Professional & Vocational Format: Paperback Publisher's Status: Active Availability: To order Stock availability from the supplier is unknown. We will order it for you and ship this item to you once it is received by us. Table of ContentsReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |