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OverviewThis presentation describes the unique anatomy and physiology of the vascular beds that serve the eye. The needs for an unobstructed light path from the cornea to the retina and a relatively fixed corneal curvature and distance between refractive structures pose significant challenges for the vasculature to provide nutrients and remove metabolic waste. To meet these needs, the ocular vascular beds are confined to the periphery of the posterior two thirds of the eye and a surrogate circulation provides a continuous flow of aqueous humor to nourish the avascular cornea, lens and vitreous compartment. The production of aqueous humor (and its ease of egress from the eye) also generates the intraocular pressure (IOP), which maintains the shape of the eye. However, the IOP also exerts a compressing force on the ocular blood vessels that is higher than elsewhere in the body. This is particularly true for the intraocular veins, which must have a pressure higher than IOP to remain patent, and so the IOP is the effective venous pressure for the intraocular vascular beds. Consequently, the ocular circulation operates at a lower perfusion pressure gradient than elsewhere in the body and is more at risk for ischemic damage when faced with low arterial pressure, particularly if IOP is elevated. This risk and the specialized tissues of the eye give rise to the fascinating physiology of the ocular circulations. Full Product DetailsAuthor: Jeffrey W. Kiel , D. Neil Granger , Joey GrangerPublisher: Morgan & Claypool Publishers Imprint: Morgan & Claypool Publishers Dimensions: Width: 19.10cm , Height: 0.40cm , Length: 23.50cm Weight: 0.180kg ISBN: 9781615041688ISBN 10: 1615041680 Pages: 81 Publication Date: 01 February 2011 Audience: College/higher education , Professional and scholarly , Undergraduate , Postgraduate, Research & Scholarly Format: Paperback Publisher's Status: Active Availability: In Print  This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us. Table of ContentsIntroduction Anatomy Blood flow measuring techniques Ocular perfusion pressure, IOP and the ocular Starling resistor effect Ocular blood flow effects on IOP Local control of ocular blood flow Neural control of ocular blood flow SummaryReviewsAuthor InformationJeffrey W. Kiel received his Ph.D. in Physiology fromthe University ofTexas Health Science Center at San Antonio in 1987. His early research focused on gastrointestinal vascular regulation, and then in 1990 he changed directions and began studying the eye. He has worked on choroidal blood flow regulation, the role of ciliary blood flow in aqueous production and, most recently, on the regulation of episcleral venous pressure. Tab Content 6Author Website:Countries AvailableAll regions |
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