Overview

A number of remarkable recent breakthroughs have made the study of nitric oxide one of the most exciting fields in physiology and pathophysiology. This authoritative edited volume reviews the progress to date and opens perspectives to novel diagnostic and therapeutic strategies. The contributors are leading authorites, in most cases the investigators who have pioneered the ideas explored in the book.

Full Product Details

Author:   Michael S. Goligorsky ,  Steven S. Gross
Publisher:   Springer-Verlag New York Inc.
Imprint:   Springer-Verlag New York Inc.
Edition:   Softcover reprint of the original 1st ed. 1997
Dimensions:   Width: 15.20cm , Height: 2.40cm , Length: 22.90cm
Weight:   0.709kg
ISBN:  

9781461377689

ISBN 10:   1461377684
Pages:   463
Publication Date:   27 September 2012
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
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Table of Contents

I. General Biochemistry of NOSs and Cellular Actions of NO.- 1. The Biological Chemistry of NO.- 2. Role of NO and Nitrogen Intermediates in Regulation of Cell Functions.- 3. Nitric Oxide Synthases and Their Cofactors.- 4. Regulation of the NOS Gene Family.- 5. Role of NO in Cell Locomotion.- II. Renal Expression of NOSs and Production of NO.- 6. Metabolic Pathways and Cycles of L-Arginine Synthesis and Utilization.- 7. Distribution of NOSs in the Kidney.- III. NO and the Regulation of Renal Hemodynamics.- 8. Vascular Effects of NO.- 9. Role of NO in the Function of the Juxtaglomerular Apparatus.- 10. NOS in Mesangial Cells: Physiological and Pathophysiological Roles.- 11. Tubuloglomerular Feedback and Macula Densa-Derived NO.- 12. NO and the Renin System.- 13. NO and the Medullary Circulation.- IV. Role of NO system in Renal Pathophysiology.- 14. NO in Septic Shock.- 15. NO and Glomerulonephritis.- 16. NO in Acute Renal Failure.- 17. NO in Diabetic Nephropathy.- 18. NO and Hypertension.- 19. NO in Normal and Preeclamptic Pregnancy.- 20. Sickle Cell Disease and NO.- 21. A Putative Role of NO and Oxidant Injury in the Pathogenesis of Hemolytic Uremic Syndrome.- 22. Role of NO in Urinary Tract Infections.- 23. Role of the NO System in Urinary Tract Obstruction.

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