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OverviewThis book summarizes 20 years of work on the kinetics of blood-brain transfer and metabolism mechanisms in mammalian brain. The substances affiliated with these mechanisms include glucose, amino acids, monocarboxylic acids, and oxygen. These substances are important to energy metabolism and neurotransmission in the mammalian brain at rest and during activation. To understand the processes addressed by these mechanisms, the book examines the kinetics of compartmentation and compartmental analysis, particularly as they relate to transporter, enzyme, and receptor function. Compartments are subsets of substances separated by transporters and receptors in membranes, and enzymes in cells. This book is divided in six major chapters covering compartmental analysis, kinetic analysis of transport and metabolism, blood-brain transfer and metabolism of glucose, amino acids, and oxygen, and amino acid metabolism and interaction of amino acid metabolites with receptors. Full Product DetailsAuthor: Albert Gjedde , William R. Bauer , Dean WongPublisher: Springer-Verlag New York Inc. Imprint: Springer-Verlag New York Inc. Edition: 2011 ed. Dimensions: Width: 15.50cm , Height: 1.90cm , Length: 23.50cm Weight: 0.557kg ISBN: 9781489981332ISBN 10: 1489981330 Pages: 343 Publication Date: 11 October 2014 Audience: Professional and scholarly , Professional & Vocational Format: Paperback Publisher's Status: Active Availability: Manufactured on demand  We will order this item for you from a manufactured on demand supplier. Table of Contents1: Introduction to Compartmental Analysis.- 2: Fundamentals of Compartmental Kinetics.- 3: Principles of Neuroreceptor Mapping in Vivo.- 4: Neuroreceptor Mapping in Vivo: Monoamines.- 5: Blood-Brain Transfer and Metabolism of Oxygen.- 6: Blood-Brain Glucose Transfer.- 7: Metabolism of Glucose.- 8: Brain Energy Metabolism.- 9: Glossary.- 10: ReferencesReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |
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