Overview

This is the first comprehensive review of all aspects of nociceptor function, including the structure of nociceptor endings, their neurochemistry, and evolutionary considerations. It deals with the functional properties of nociceptors innervating different organs and the biophysical mechanisms underlaying the transduction process in nociceptors. There are sections on how nociceptor function is modified by nerve injury and regeneration and on its physiopathology.This is an essential reference for researchers in neuroscience and pharmacology, and clinicians working in pain management.

Full Product Details

Author:   Carlos Belmonte (Professor, Professor, University of Alicante) ,  Fernando Cervero (Professor, Professor, University of Alcala de Henares)
Publisher:   Oxford University Press
Imprint:   Oxford University Press
Dimensions:   Width: 17.50cm , Height: 3.50cm , Length: 25.10cm
Weight:   1.225kg
ISBN:  

9780198523345

ISBN 10:   0198523343
Pages:   542
Publication Date:   01 August 1996
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   To order  
Stock availability from the supplier is unknown. We will order it for you and ship this item to you once it is received by us.

Table of Contents

Preface B. Lynn: Principles of classification and nomenclature relevant to studies of nociceptive neurones Part 1: Basic aspects of nociceptor function 1: E. Perl: Pain and the discovery of nociceptors 2: L. Kruger and Z. Halata: Structure of nociceptor 'endings' 3: S. Lawson: Neurochemistry of cutaneous nociceptors 4: E. Walters: Comparative and evolutionary aspects of nociceptor function Part 2: Nociceptors and the signalling of injury 5: J. Campbell and R. Meyer: Cutaneous nociceptors 6: C. Belmonte and J. Gallar: Corneal nociceptors 7: S. Mense: Nociceptors in skeletal muscle and their reaction to pathological tissue changes 8: H. Schaible and R. Schmidt: Neurobiology of articular nociceptors 9: F. Cervero: Visceral nociceptors Part 3: Transduction mechanisms and sensitization 10: C. Belmonte: Signal transduction in nociceptors: general principles 11: M. Kress and P. Reeh: Chemical excitation and sensitization in nociceptors 12: S. Bevan: Intracellular messengers and signal transduction in nociceptors 13: T. Kumazawa: Sensitization of polymodal receptors Part 4: Functions of nociceptors 14: E. Torebj ork, M. Schmelz and H. Handwerker: Functional properties of human cutaneous nociceptors and their role in pain and hyperalgesia 15: R. Meyer, S. Raja and J. Campbell: Neural mechanisms of primary hyperalgesia 16: R. LaMotte: Secondary cutaneous dysaesthesiae 17: B. Lynn: Efferent function of nociceptors 18: C. Stein: Nociceptors and neuroimmune interactions Part 5: Nociceptor plasticity 19: L. Mendell: Development of the nociceptor phenotype: role of nerve growth factor 20: S. Lisney: Properties of regenerated nociceptor afferents 21: J. Ochoa, J. Serra and M. Campero: Pathophysiology of human nociceptor function

Reviews

a compilation of detailed chapters, which attempts and succeeds as a thorough review of the literature pertaining to nociceptors up to 1995 ... the book is well organized and carefully written and edited so that it remains readable and thought-provoking throughout ... a comprehensive source text that provides appropriately referenced key concepts of contemporary research involving nociceptors, and brings into focus current perspectives for understanding their role in pain perception * Karin N. Westlund, Marine Biomedical Institute, Galveston, TINS, Vol. 20, No. 6, 1997 *

a compilation of detailed chapters, which attempts and succeeds as a thorough review of the literature pertaining to nociceptors up to 1995 ... the book is well organized and carefully written and edited so that it remains readable and thought-provoking throughout ... a comprehensive source text that provides appropriately referenced key concepts of contemporary research involving nociceptors, and brings into focus current perspectives for understanding their role in pain perception Karin N. Westlund, Marine Biomedical Institute, Galveston, TINS, Vol. 20, No. 6, 1997

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