Neural Tube Defects and Genetic Polymorphisms

Author:   Helmi Y Al Farra
Publisher:   LAP Lambert Academic Publishing
ISBN:  

9783844333961


Pages:   116
Publication Date:   28 April 2011
Format:   Paperback
Availability:   In stock   Availability explained
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Neural Tube Defects and Genetic Polymorphisms


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Overview

The neural tube is the embryonic precursor of the brain and the spinal cord. Building a neural tube is an extremely complex phenomenon where cells need to change in shape, migrate and differentiate to form a hollown tube from a flat sheet of thickened epithelial cells (the neural plate). The normal closure of the neural plate occurs very early in human pregnancy from day 21 until day 28 following conception or 1 weak after the expected menstruation. Abnormal closure of the neural plate results in neural tube defects (NTDs). The orrelation between the birth of NTD affected children and the maternal polymorphisms of two genes related to the folate metabolic pathway, studied methylenetetrahydrofolate-dehydrogenase (MTHFD1) 1958 (G>A) and methionine synthase polymorphisms MTR 2756 (A>G) and MTR 2758(C>G) in the Jordanian population have been examined in this original study.

Full Product Details

Author:   Helmi Y Al Farra
Publisher:   LAP Lambert Academic Publishing
Imprint:   LAP Lambert Academic Publishing
Dimensions:   Width: 15.20cm , Height: 0.70cm , Length: 22.90cm
Weight:   0.181kg
ISBN:  

9783844333961


ISBN 10:   3844333967
Pages:   116
Publication Date:   28 April 2011
Audience:   General/trade ,  General
Format:   Paperback
Publisher's Status:   Active
Availability:   In stock   Availability explained
We have confirmation that this item is in stock with the supplier. It will be ordered in for you and dispatched immediately.

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