Nervous System Regeneration in the Invertebrates

Author:   Stacia B. Moffet
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Edition:   Softcover reprint of the original 1st ed. 1996
Volume:   34
ISBN:  

9783642798412


Pages:   208
Publication Date:   14 December 2011
Format:   Paperback
Availability:   Manufactured on demand   Availability explained
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Nervous System Regeneration in the Invertebrates


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Overview

Invertebrate animals represent a diversity of solutions to life's challenges. Success in a wide range of environments has been achieved by an almost bewildering range of invertebrate body forms. These body forms are reflected in the wonderful diversity of their nervous systems. Despite this apparent diversity, studies of the development of invertebrates and vertebrates are yielding common themes at the molecular level. Likewise, the phenome­ non of neural regeneration is based upon properties intrinsic to neurons and responses to a remarkably conserved chemical lan­ guage. This monograph focuses on the diversity and commonal­ ity of responses to neural injury. The rough and tumble of life may frequently damage some part of the body, particularly the appendages or sensory sys­ tems. The nervous system is usually involved in repair of other body systems and often may itself require repair. Some animals are particularly successful in regenerating the nervous system or body parts. We particularly marvel at these feats of regeneration because we human beings are not particularly successful, despite our relatively long life and the advantages that would seem to accrue from such repair. It is no wonder that we would hope to learn the secrets of the more successful animals and strive to emulate them! Mechanisms of neural regeneration are often more acces­ sible in invertebrates than in vertebrates because questions of specificity are more easily addressed using the identifiable neu­ rons of the relatively simpler nervous systems of some inverte­ brates.

Full Product Details

Author:   Stacia B. Moffet
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Imprint:   Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Edition:   Softcover reprint of the original 1st ed. 1996
Volume:   34
Dimensions:   Width: 15.50cm , Height: 1.20cm , Length: 23.50cm
Weight:   0.347kg
ISBN:  

9783642798412


ISBN 10:   3642798411
Pages:   208
Publication Date:   14 December 2011
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand   Availability explained
We will order this item for you from a manufactured on demand supplier.

Table of Contents

1 The Phenomenon of Neural Regeneration.- 1.1 How Shall We Define Neural Regeneration?.- 1.2 Replacement of Neurons.- 1.3 Regrowth of Neurites.- 1.4 A Cost-Benefit Analysis of Neural Regeneration.- 1.5 Rationale for Studying Invertebrate Regeneration.- 1.6 Conclusions.- 2 A Survey of Neural Repair in Invertebrates.- 2.1 Introduction.- 2.2 Cnidaria: Neural Structure and Behavior.- 2.3 Ctenophora: Comb Jellies.- 2.4 Platyhelminthes: The Simplest Bilateral Nervous System.- 2.5 Nemertea: Ribbon Worms.- 2.6 Nematoda: Roundworms.- 2.7 Annelida: Introduction to the Phylum.- 2.8 Arthropoda: Neural Organization and Repair.- 2.9 Mollusca: Unsegmented Animals with a Range of Cephalization.- 2.10 Echinodermata: The Spiny Deuterostomes.- 2.11 Chordata: Our Own Phylum.- 3 Early Responses to Neural Injury.- 3.1 Introduction.- 3.2 Immediate Responses of Injured Neurons.- 3.3 Growth Following Axotomy.- 3.4 Survival of Anucleate Axon Segments.- 3.1 Responses of Nonneural Cells to Injury.- 3.2 What Activates Responses in Uninjured Neurons?.- 3.3 Conclusions.- 4 Pathfinding by the Growth Cone.- 4.1 Introduction.- 4.2 Growth Cone Morphology.- 4.3 Growth Cone Extension.- 4.4 Ion Channels in the Growth Cone.- 4.5 Responses of Growth Cones to Neurotransmitters.- 4.6 Differentiation Following Growth Cone Interactions.- 4.7 Receptors and Molecular Cues in the Environment.- 4.8 Conditioned Medium and Growth Promotors.- 4.9 Designing Culture Conditions.- 5 Synapse Formation and Alteration During Regeneration.- 5.1 Introduction.- 5.2 The Road to Recovery.- 5.3 How Neurons Select Targets.- 5.4 Development of a Functioning Synapse.- 5.5 The Role of Competition.- 5.6 Conclusions.- References.

Reviews

. ..an excellent and long-overdue summary of cell-body and axonal regeneration of neurons in many invertebrate phyla. TINS


...an excellent and long-overdue summary of cell-body and axonal regeneration of neurons in many invertebrate phyla. TINS


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