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OverviewNatural Hosts of SIV: Implications in AIDS thoroughly reviews the possible mechanisms by which African nonhuman primate natural hosts of lentiviruses remain essentially disease-free while other hosts exhibit disease and death. The book ultimately indicates directions for further research and potential translations of this compelling phenomenon into novel approaches to treat and prevent HIV. When Asian non-human primate non-natural hosts are experimentally infected with viruses isolated from African species, disease and death normally results. Meanwhile, these African nonhuman primate natural hosts maintain similar levels of plasma and cellular viremia and exhibit compellingly different, essentially disease-free, states. This work attempts to answer the question of how the natural host remains disease resistant. Full Product DetailsAuthor: Aftab A. Ansari (Emory University & Yerkes National Primate Research Center, Atlanta, GA, USA) , Guido Silvestri (Emory University and Yerkes National Primate Research Center, Atlanta, GA, USA)Publisher: Elsevier Science Publishing Co Inc Imprint: Elsevier Science Publishing Co Inc Dimensions: Width: 15.20cm , Height: 2.30cm , Length: 22.90cm Weight: 0.860kg ISBN: 9780124047341ISBN 10: 0124047343 Pages: 400 Publication Date: 06 August 2014 Audience: Professional and scholarly , Professional & Vocational Format: Hardback Publisher's Status: Active Availability: Manufactured on demand  We will order this item for you from a manufactured on demand supplier. Table of Contents1. Overview Aftab Ansari and Guido Silvestri 2. Historical perspective Preston Marx 3. SIV infections in the wild Cristian Apetrei and Martine Peeters 4. Virology of SIVs Frank Kirchhoff 5. SIV infection of chimpanzees Jonathan Heeney, Edward James Donald Greenwood and Fabian Schmidt 6. Pathology of acute & chronic infection Francois Villinger and Sanjeev Gumber 7. Mucosal immunity Jason Brenchley 8. Innate immunity Steven E. Bosinger and R. Keith Reeves 9. Humoral immune responses Cynthia Ann Derdeyn and Reinhard Kurth 10. Cellular immune responses Amitinder Kaur 11. Chronic immune activation Donald Sodora 12. Pattern of infected cells Mirko Paiardini and Thomas Howerton Vanderford V 13. Viral transmission Ivona Pandrea and Ann Chahroudi 14. Genetics of the host Lutz Walter 15. The different modes of HIV/SIV control in monkeys and humans Lisa Chakrabarti 16. Humans resembling natural hosts Amalio Telenti and Paul McLaren Epilogue: Implications for HIV infection Aftab Ansari and Guido SilvestriReviewsAuthor InformationAftab Ansari, Ph.D. Dr. Aftab A. Ansari, Professor, Department of Pathology and Laboratory Medicine, Room 2309 WMB, Emory University School of Medicine, 101 Woodruff Circle, Atlanta, GA 30322, USAPh.D., University of Arizona, Tucson, Arizona, 1970 M.S., University of California, Los Angeles, CA, 1967 M.S., University of Karachi, Karachi, Pakistan, 1963 B.S., University of Karachi, Karachi, Pakistan, 1961 1981-present Senior Consultant, Naval Medical Research and Development Command, Bethesda, Maryland1985-Present Professor, Department of Pathology and Laboratory Medicine, Emory University1999-present Scientific Advisor, U.S. Naval Medical Research Unit #2, Jakarta, Indonesia.2002-present Scientific Advisory Board, One World Health, San Francisco, CA.2001-2008 Scientific Advisory Board, Lipid Sciences, Inc. Pleasanton, CA.2005-present Scientific External Advisory Board member, CAHDR, Meharry Medical College, Nashville, TN2008-present Scientific Advisory Board, SMART Technologies, Inc., Rehovot, Israel2007-present Member, FDA Expert Panel, FDA Center for Devices and Radiological Health (CDRH), SGE, Deptt. Of Health & Human Services, Immunology Devices Panel Professor Pathology and Laboratory Medicine, Emory University, Atlanta, GA, USAChief, Division of Microbiology and Immunology, Yerkes National Primate Research Center Georgia Research Alliance Eminent Scholar in Comparative Pathology, Emory University Tab Content 6Author Website:Countries AvailableAll regions |
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