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Overview"Po dannym VOZ ot tuberkuleza ezhegodno umirayut bolee dvukh millionov chelovek vo vsem mire. Tuberkulez ob""yavlen vsemirnoy opasnost'yu. Bol'shinstvo infektsionnykh zabolevaniy otnosyat k mul'tifaktorial'noy patologii, kotoraya predstavlyaet soboy rezul'tat slozhnogo vzaimodeystviya bol'shogo chisla genov s raznoobraznymi faktorami okruzhayushchey sredy. K gruppe genov-kandidatov tuberkuleza otnosyat gen makrofagal'nogo belka, assotsiirovannogo s estestvennoy rezistentnost'yu (NRAMP1), gen retseptora k vitaminu D (VDR), gen interleykina-1β (IL1B) i ego retseptornogo antagonista (IL1RN), gen interleykina-12β i drugie. Odnim iz metodov analiza roli geneticheskikh faktorov v vozniknovenii i razvitii rasprostranennykh zabolevaniy yavlyaetsya issledovanie assotsiatsiy geneticheskikh markerov s bolezn'yu. V knige predstavleny svedeniya o rasprostranennosti allel'nykh variantov genov NRAMP1, VDR, IL12B, IL1B, IL1RN, proveden mezhpopulyatsionnyy sravnitel'nyy analiz genov-kandidatov tuberkuleza, izucheno ikh vliyanie na vozniknovenie i razvitie razlichnykh klinicheskikh variantov zabolevaniya, pokazana svyaz' polimorfizma genov s kachestvennymi i kolichestvennymi kharakteristikami tuberkuleza. genetikam, ftiziatram" Full Product DetailsAuthor: Kolokolova O V , Puzyrev V PPublisher: LAP Lambert Academic Publishing Imprint: LAP Lambert Academic Publishing Dimensions: Width: 15.20cm , Height: 0.80cm , Length: 22.90cm Weight: 0.204kg ISBN: 9783659360060ISBN 10: 3659360066 Pages: 132 Publication Date: 26 March 2013 Audience: General/trade , General Format: Paperback Publisher's Status: Active Availability: In stock  We have confirmation that this item is in stock with the supplier. It will be ordered in for you and dispatched immediately. Language: Russian Table of ContentsReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |
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