Overview

This book presents the role of nanoparticles in cancer therapy, emphasizing their innovative applications across treatment, diagnosis and the development of therapeutic strategies. The first section of the book describes the applications of nanoparticles in cancer vaccines and gene therapy. It features discussions on polymeric nanoparticles as nanovaccine carriers, membrane-based nano-vaccines for immunotherapy and gene therapy techniques employing nanoparticles. The second section presents advanced nanomedicine approaches, specifying the role of chemodynamic nanoparticles in cancer theranostics, the application of low-dimensional nanomaterials and emerging strategies against drug resistance. Additionally, it explores nanotechnology in radiation therapy, phototherapy modalities and bioengineered virus-like nanoparticles for diagnostics and therapeutics. The last section reviews the clinical applications and prospects, examining theranostic nanoparticles, the clinical translation of nanomedicine and the current limitations of cancer nanotherapy. It also addresses future directions in nanoparticle application, and examines the genotoxicity, immunotoxicity, cytotoxicity assessments, safety profiles, targeted drug delivery, and their role in viral oncogenesis. This book is a useful resource for researchers, clinicians and students in the fields of oncology and nanotechnology.

Full Product Details

Author:   Neelam Thakur ,  Bhukya Prudhvi Lal
Publisher:   Taylor & Francis Ltd
Imprint:   CRC Press
ISBN:  

9781032849171

ISBN 10:   1032849177
Pages:   322
Publication Date:   08 November 2024
Audience:   College/higher education ,  Professional and scholarly ,  Tertiary & Higher Education ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Forthcoming
Availability:   Not yet available  
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Table of Contents

Chapter 1. Introduction to Cancer Biology. Chapter 2. Nanoparticles used in cancer therapy. Part II: Nanoparticles in Cancer Vaccines and Gene Therapy. Chapter 3. Polymeric nanoparticles as nanovaccine carriers for eliciting anticancer immunity. Chapter 4. Membrane-Based Nano-Vaccines for Immunotherapy. Chapter 5. Gene Therapy Utilizing Nanoparticles. Part III: Advanced Nanomedicine Approaches. Chapter 6. From Diagnosis to Treatment: The Role of Chemodynamic Nanoparticles in Cancer Theranostics. Chapter 7. Low-Dimensional Nanomaterials as an Emerging Platform for Cancer Diagnosis and Therapy. Chapter 8. Emerging Nano-based Strategies for Managing Drug Resistance in Cancer. Chapter 9. Nanotechnology-based Radiation Therapy to Cure Cancer. Chapter 10. Phototherapy Modalities Empowered by Nanotechnology. Chapter 11. Bioengineered Virus-Like Nanoparticles for Cancer Diagnostics and Therapeutics. Part IV: Clinical Applications and Future Prospects. Chapter 12. Theranostic Nanoparticles: Revolutionizing Cancer Diagnosis and Treatment. Chapter 13. Anti-Cancer Nanotherapeutics in Clinical Trials: The Work Behind Clinical Translation of Nanomedicine. Chapter 14. Limitations of Cancer Nanotherapy: Present Status and Future Prospects. Chapter 15. Current Challenges and Future Prospects in Nanoparticle Application. Chapter 16. Assessment of Genotoxicity and Immunotoxicity Nanoparticles: Overview and testing methods. Chapter 17. Assessment of Nanoparticles Induced Cytotoxicity and Safety Profiles. Chapter 18. Nanotechnology in Cancer Therapy: Targeted Drug Delivery and the Role in Viral Oncogenesis

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Author Information

Prudhvi Lal Bhukya is a Virologist currently serving at ICMR-National Animal Resource Facility for Biomedical Research (NARFBR), Hyderabad, as a Scientist. Presently, he is associated with the preclinical vaccine testing laboratory at NARFBR. His areas of work include preclinical vaccinology studies, hostviral interaction studies of emerging human viral infections, and the prevention and control of diseases, as well as the development of tools to prevent outbreaks. He obtained his Ph.D. from ICMR-National Institute of Virology, Pune, on human hepatitis B virus. He proved his credentials by working on HBV and HEV with an extensive publication record. He has presented his work at numerous national and international conferences and has received accolades with several publications in international journals like the Journal of General Virology, Journal of Virology, Journal of Travel Medicine, Indian Journal of Medical Microbiology and Science of Total Environment. He is an experienced manuscript writer and has contributed to several book chapters for publication bodies like Springer Nature, CRC Press, IntechOpen, IGI Global Publications, etc. Dr. Prudhvi also edited a book in Springer Nature entitled “Emerging Human Viral Disease” in two volumes. His contribution to these books as an editor will act as a catalyst, as his comments are highly critical and an achievement for the book. Neelam Thakur is currently working as an Assistant Professor in the Department of Zoology at Sardar Patel University (a State Govt. University), Mandi, Himachal Pradesh, India since 2022. Before joining this university, she worked as an Associate Professor in the Department of Biosciences at Chandigarh University, Punjab, India. She obtained her Ph.D. in Genetics from Himachal Pradesh University in 2012. After her Ph.D., she joined as a Research Associate in the Immunology lab of CSIR-IMTECH, Chandigarh in 2012. Her research interests include the early diagnosis of tuberculosis and cancer, nanotechnology for cancer diagnostics and therapy, cytogenetic analysis of intellectually disabled individuals and microbiome studies. She has supervised many master’s students and is currently guiding Ph.D. students as well. She has published 18 research papers in journals with good impact factors, such as “Cellular Signaling”. Her patent, entitled “ANTIGENIC COMPOSITION AND METHOD OF EXPRESSION THEREOF”, was also published. She has received two Young Researchers Awards and one Eminent Researchers Award from government-registered societies/ organizations for her contribution to research.

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