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OverviewFull Product DetailsAuthor: Giovanna Scapin , Disha Patel , Eddy ArnoldPublisher: Springer Imprint: Springer Dimensions: Width: 15.50cm , Height: 1.30cm , Length: 23.50cm Weight: 3.869kg ISBN: 9789401797245ISBN 10: 9401797242 Pages: 240 Publication Date: 12 March 2015 Audience: Professional and scholarly , Professional & Vocational Format: Paperback Publisher's Status: Active Availability: Manufactured on demand  We will order this item for you from a manufactured on demand supplier. Table of ContentsPreface.- List of Contributors.- Engineering G Protein-Coupled Receptors for Drug Design.- Structural Insights into Activation and Allosteric Modulation of G Protein-Coupled Receptors.- Epigenetic Drug Discovery.- Crystallography and Biopharmaceuticals.- Structural Chemistry and Molecular Modeling in the Design of DPP4 Inhibitors.- Considerations for Structure-Based Drug Design Targeting HIV-1 Reverse Transcriptase.-Protein-Ligand Interactions as the Basis for Drug Action.- The Protein Data Bank: Overview and Tools for Drug Discovery.- Small Molecule Crystal Structures in Drug Discovery.- Protein Aggregation and its Prediction.- Importance of Protonation States for the Binding of Ligands to Pharmaceutical Targets.- Protein-Protein Interactions: Structures and Druggability.- Achieving High Quality Ligand Chemistry in Protein-Ligand Crystal Structures for Drug Design.- Molecular Obesity, Potency and Other Addictions in Drug Discovery.- Adventures in Small Molecule Fragment Screening by X-ray Crystallography for Drug Discovery.- Structure-Based Drug Design to Perturb Function of a tRNA-Modifying Enzyme by Active Site and Protein-Protein Interface Inhibition.- Molecular Interaction Analysis for Discovery of Drugs Targeting Enzymes and for Resolving Biological Function.ReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |
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