MTHFR and acute lymphoblastic leukemia: a meta-analysis

Author:   Rim Frikha
Publisher:   Our Knowledge Publishing
ISBN:  

9786203477146


Pages:   76
Publication Date:   13 March 2021
Format:   Paperback
Availability:   In stock   Availability explained
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MTHFR and acute lymphoblastic leukemia: a meta-analysis


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Overview

Genetic polymorphisms result from common, often benign mutations; however, some are considered markers of susceptibility to certain multifactorial conditions. This is the case for 5,10-methylene tetrahydrofolate reductase (MTHFR); a key enzyme in folate metabolism. Its role in the risk of acute lymphoblastic leukemia(ALL); the most common form of pediatric cancers; has generated significant interest.Thus, our research work focused on exploring, through an updated meta-analysis, the involvement of MTHFR polymorphisms in susceptibility to FAL.It is possible that MTHFR variants contribute only modestly to the emergence of LAL, but it is also possible that their interactions with other factors could elucidate the cause of this complex pathology.Thus, analysis of these polymorphisms will promote nutrigenetics as long as the gene complexity and metabolic activities of MTHFR are taken into consideration.

Full Product Details

Author:   Rim Frikha
Publisher:   Our Knowledge Publishing
Imprint:   Our Knowledge Publishing
Dimensions:   Width: 15.20cm , Height: 0.50cm , Length: 22.90cm
Weight:   0.122kg
ISBN:  

9786203477146


ISBN 10:   6203477141
Pages:   76
Publication Date:   13 March 2021
Audience:   General/trade ,  General
Format:   Paperback
Publisher's Status:   Active
Availability:   In stock   Availability explained
We have confirmation that this item is in stock with the supplier. It will be ordered in for you and dispatched immediately.

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