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Overview""The laboratory mouse is an important model for studying cancer and its treatment. This book includes both background information and step-by-step protocols for generating mouse models that accurately recapitulate many features of human cancer. It covers genetic models, including transgenic germline models, gene knockouts and knockins, and conditional and inducible systems, as well as models derived using chemical carcinogens, RNA interference, tissue recombination, and other strategies. Techniques to characterize tumor development, progression, and metastasis in these mice using state-of-the-art imaging, histopathological, surgical, and other approaches are described. The uses of these models in preclinical and translational research are also discussed""-- Full Product DetailsAuthor: Cory Abate-Shen , Katerina Politi , Lewis Chodosh , Kenneth P OlivePublisher: Cold Spring Harbor Laboratory Press,U.S. Imprint: Cold Spring Harbor Laboratory Press,U.S. Dimensions: Width: 21.80cm , Height: 2.40cm , Length: 27.50cm Weight: 1.465kg ISBN: 9781621820031ISBN 10: 1621820033 Pages: 521 Publication Date: 30 November 2013 Audience: General/trade , General Format: Paperback Publisher's Status: Active Availability: In stock  We have confirmation that this item is in stock with the supplier. It will be ordered in for you and dispatched immediately. Table of ContentsReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |
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