Mouse Genetics and Transgenics: A Practical Approach

Author:   Ian J. Jackson (, MRC Human Genetics Unit, Edinburgh) ,  Cathy Abbott (, Human Genetics Unit, Dept of Medical Sciences, University of Edinburgh)
Publisher:   Oxford University Press
Volume:   217
ISBN:  

9780199637089


Pages:   324
Publication Date:   09 December 1999
Format:   Paperback
Availability:   To order   Availability explained
Stock availability from the supplier is unknown. We will order it for you and ship this item to you once it is received by us.

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Mouse Genetics and Transgenics: A Practical Approach


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Overview

A unique book that integrates knowledge from a wide range of expertise, specifically applied to the mouse, and addressed at a wide audience from those new to the field to experts who want an update on the state of the art. Mouse Genetics and Transgenics: APA covers all aspects of using the mouse as a genetic model organism: care & husbandry; archiving stocks as frozen embryos or sperm; making new mutations by chemical mutagenesis; transgenesis; and gene targetting; mapping mutations and polygenic traits by cytogenetic, genetic, and physical means; and disseminating and researching information via the Internet.

Full Product Details

Author:   Ian J. Jackson (, MRC Human Genetics Unit, Edinburgh) ,  Cathy Abbott (, Human Genetics Unit, Dept of Medical Sciences, University of Edinburgh)
Publisher:   Oxford University Press
Imprint:   Oxford University Press
Volume:   217
Dimensions:   Width: 15.80cm , Height: 1.80cm , Length: 23.50cm
Weight:   0.506kg
ISBN:  

9780199637089


ISBN 10:   0199637083
Pages:   324
Publication Date:   09 December 1999
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   To order   Availability explained
Stock availability from the supplier is unknown. We will order it for you and ship this item to you once it is received by us.

Table of Contents

Hetherington, Doe and Hay, mouse care and husbandry; Glenister and Rall, cryopreservation and rederivation of embryos and gametes; Nonchev and Maconochie, spatial analysis of gene expression; Maine, mapping phenotypic trait loci; Denny and Brown, mapping genomes; Akeson et al, mouse cytogenetics and FISH; Eppig, electronic tools for accessing the mouse genome; Justice, mutagenesis of the mouse germline; Hammes and Schedl, generation of transgenic mice from plasmids, BACs and YACS; Plagge, Kelsey and Allen, directed mutagenesis in embryonic stem cells.

Reviews

provides a major source of information on the mouse as an experimental model, and can be used as a detailed manual for researchers ... offers tried-and-tested protocols, with handy trouble-shooting tips and other supporting advice. It is aimed for both scientists new to the field and those who want an overview of the latest techniques. Index at the end of the book facilitates quick orientation and selective reading. Croatian Medical Journal (CMJ) We give a thumbs up to a book already well thumbed and in use in the lab. The Genetical Society of Great Britain


... provides a major source of information on the mouse as an experimental model, and can be used as a detailed manual for researchers ... offers tried-and-tested protocols, with handy trouble-shooting tips and other supporting advice. It is aimed for both scientists new to the field and those who want an overview of the latest techniques. Index at the end of the book facilitates quick orientation and selective reading. Croatian Medical Journal (CMJ) We give a thumbs up to a book already well thumbed and in use in the lab. The Genetical Society of Great Britain


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