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OverviewA Unified Microscopic Approach to Analyzing Complex Processes in Molecular Motors Motor Proteins and Molecular Motors explores the mechanisms of cellular functioning associated with several specific enzymatic molecules called motor proteins. Motor proteins, also known as molecular motors, play important roles in living systems by supporting cellular transport and force generation via the transformation of chemical energy into mechanical work. The book presents established results, theoretical methods, and experimental observations related to biological molecular motors. It uses fundamental physical-chemical concepts and methods to develop a systematic theoretical framework for understanding motor protein dynamics. The author introduces the main ideas using simple arguments that avoid heavy mathematical derivations in favor of more intuitive physical understanding. Although the book assumes some rudimentary knowledge of cell biology, calculus, and basic ideas from chemistry and physics, it gives explanations and derivations for most results. Accessible to students and researchers in a wide range of scientific fields, this book provides a unified molecular picture for analyzing motor proteins. It connects major experimental facts on molecular motors to principal theoretical concepts consistent with the fundamental laws of chemistry and physics. Full Product DetailsAuthor: Anatoly B. KolomeiskyPublisher: Taylor & Francis Inc Imprint: CRC Press Inc Dimensions: Width: 15.60cm , Height: 1.80cm , Length: 23.40cm Weight: 0.453kg ISBN: 9781482224757ISBN 10: 1482224755 Pages: 222 Publication Date: 28 April 2015 Audience: College/higher education , College/higher education , Postgraduate, Research & Scholarly , Tertiary & Higher Education Format: Hardback Publisher's Status: Active Availability: In Print  This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us. Table of ContentsIntroduction. Basic Properties of Motor Proteins. Experimental Studies of Motor Proteins. Fundamental Physical Concepts: Equilibrium Approaches. Fundamental Physical Concepts: Non-Equilibrium Approaches. Motor Proteins as Enzymes. Theory for Motor Proteins: Continuum Ratchets. Theory for Motor Proteins: Discrete-State Stochastic Models. Collective Properties of Motor Proteins. Artificial Molecular Motors and Rotors. Future Directions in Studies of Motor Proteins and Molecular Motors. Index.ReviewsAs a chemical physicist dabbling in molecular biophysics, I am particularly intimidated by the subject of molecular machines. Reading much of what is written on this subject is like trying to understand how the internal combustion engine works by looking at the blueprints of a modern car engine, with the added difficulty of the blueprints often being inaccurate or incomplete. In contrast, Kolomeisky goes straight into the heart of the matter and explains why and how fundamental principles of physics and chemistry allow those marvelous molecular assemblies to generate directional motion and to perform every mechanical task in the living organism or cell. The author further describes how this molecular motion is studied experimentally, develops quantitative models that explain experimental observations, and provides a succinct, self-contained, and lucid introduction to the fundamentals of thermodynamics, statistical mechanics, and chemical kinetics relevant to molecular motors as well as to many other biochemical processes. The historical bits dispersed throughout the text make it especially refreshing to read and would be appreciated by any reader who, like myself, is amazed by the progress science has made in understanding the complexity of life. -Dmitrii Makarov, Department of Chemistry, The University of Texas at Austin Author InformationAnatoly B. Kolomeisky Tab Content 6Author Website:Countries AvailableAll regions |
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