Overview

Mutations can cause diseases by producing functionally altered proteins, and understanding the exact nature of diseases from the structures of the proteins involved is the aim of this book. It provides insights into the structures and functions of 130 of of the most important biomolecules and their interactions with other endogenous or exogenous molecules. These interactions are illustrated by three-dimensional images of their atomic structures rather than by abstract formulas or acronyms. The author has compiled a collection of molecules which he has visualized in pictures by applying molecular modelling software to their atomic coordinate files (deposited in the Brookhaven Protein Data Bank, PDB). Together with short explanatory texts they provide the reader with a deepened understanding of biological phenomena in the normal as well as the diseased organism. Following a didactic approach, this book distills the most important facts, making it accessible to the non-specialist reader as well; at the same time it serves as a guide to the vast amount of information stored in authoritative Internet databases such as the PDB and OMIM (Online Mendelian Inheritance in Men) databanks. For an in-depth study of structures and genetic diseases, an enhanced index listing databank accession numbers, gene name and chromosomal location of each molecule under consideration is added, which can also be accessed online on the book's website. A list of useful Internet resources rounds off the practical value of this textbook. Mutations can cause diseases by producing functionally altered proteins, and understanding the exact nature of diseases from the structures of the proteins involved is the aim of this book.

Full Product Details

Author:   S. Schwarz
Publisher:   S Karger AG
Imprint:   S Karger AG
Dimensions:   Width: 21.60cm , Height: 1.30cm , Length: 28.00cm
Weight:   0.900kg
ISBN:  

9783805573955

ISBN 10:   3805573952
Pages:   144
Publication Date:   24 September 2002
Audience:   College/higher education ,  Professional and scholarly ,  Undergraduate ,  Postgraduate, Research & Scholarly
Format:   Hardback
Publisher's Status:   Active
Availability:   Awaiting stock  
The supplier is currently out of stock of this item. It will be ordered for you and placed on backorder. Once it does come back in stock, we will ship it out for you.

Table of Contents

Reviews

Author Information

Tab Content 6

Author Website:  

Customer Reviews

Recent Reviews

No review item found!

Add your own review!

Countries Available

All regions