Overview

Molecular Tools and Infectious Disease Epidemiology examines the opportunities and methodologic challenges in the application of modern molecular genetic and biologic techniques to infectious disease epidemiology. The application of these techniques dramatically improves the measurement of disease and putative risk factors, increasing our ability to detect and track outbreaks, identify risk factors and detect new infectious agents. However, integration of these techniques into epidemiologic studies also poses new challenges in the design, conduct, and analysis. This book presents the key points of consideration when integrating molecular biology and epidemiology; discusses how using molecular tools in epidemiologic research affects program design and conduct; considers the ethical concerns that arise in molecular epidemiologic studies; and provides a context for understanding and interpreting scientific literature as a foundation for subsequent practical experience in the laboratory and in the field. The book is recommended for graduate and advanced undergraduate students studying infectious disease epidemiology and molecular epidemiology; and for the epidemiologist wishing to integrate molecular techniques into his or her studies.

Full Product Details

Author:   Betsy Foxman (Professor of Epidemiology, University of Michigan School of Public Health; Director, Center for Molecular and Clinical Epidemiology of Infectious Diseases, Ann Arbor, MI, USA.)
Publisher:   Elsevier Science Publishing Co Inc
Imprint:   Academic Press Inc
Dimensions:   Width: 21.60cm , Height: 2.00cm , Length: 27.60cm
Weight:   0.930kg
ISBN:  

9780123741332

ISBN 10:   0123741335
Pages:   240
Publication Date:   11 March 2011
Audience:   College/higher education ,  Tertiary & Higher Education
Replaced By:   9780443214714
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

1. Introduction and Historical Perspective 2. How Molecular Tools Enhance Epidemiologic Studies 3. Applications of Molecular Tools to Infectious Disease Epidemiology 4. A Primer of Epidemiologic Study Designs 5. A Primer of Molecular Biology  6. Molecular Tools 7. Omics Analyses in Molecular Epidemiologic Studies 8. Determining the Reliability and Validity and Interpretation of a Measure in the Study Populations 9. Designing and Implementing a Molecular Epidemiologic Study 10. Study Conduct 11. Think About Data Analysis When Planning a Study 12. Human and Animal Subject Protection, Biorepositories, Biosafety Considerations, and Professional Ethics 13 Future Directions

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Author Information

Dr. Betsy Foxman is the Hunein F. and Hilda Maassab Professor of Epidemiology, Director of the Center for Molecular and Clinical Epidemiology of Infectious Diseases (MAC-EPID), Director of the Integrated Training in Microbial Systems (ITiMS) program, and Director of the Certificate Program in Healthcare Associated Infection Prevention and Control (CHIP) at the University of Michigan. Foxman received her Bachelor of Science in Conservation of Natural Resources from the University of California, Berkeley, and MSPH and PhD in Epidemiology from the UCLA School of Public Health. Foxman studies the transmission, pathogenesis, ecology, and evolution of infectious agents with an emphasis on transmission. Current research projects include studies of the interactions between viral infections and microbiota, vaginal microbiota and pre-term birth, the oral microbiota and dental health, and epidemiology of antibiotic resistant bacteria.

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