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OverviewThis book concisely reviews our current understanding of hypoxia, molecular targeting, DNA repair, cancer stem cells, and tumor pathophysiology, while also discussing novel strategies for putting these findings into practice in daily clinical routine. Radiotherapy is an important part of modern multimodal cancer treatment, and the past several years have witnessed not only substantial improvements in radiation techniques and the use of new beam qualities, but also major strides in our understanding of molecular tumor biology and tumor radiation response. Against this backdrop, the book highlights recent efforts to identify reasonable and clinically applicable biomarkers using broad-spectrum tissue microarrays and high-throughput systems biology approaches like genomics and epigenomics. In particular, it describes in detail how such molecular information is now being exploited for diagnostic imaging and imaging throughout treatment using the example of positron emission tomography.By discussing all these issues in the context of modern radiation oncology, the book provides a broad, up-to-date overview of the molecular aspects of radiation oncology that will hopefully foster its further optimization. Full Product DetailsAuthor: Michael Baumann , Mechthild Krause , Nils CordesPublisher: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG Imprint: Springer-Verlag Berlin and Heidelberg GmbH & Co. K Edition: 1st ed. 2016 Volume: 198 Dimensions: Width: 15.50cm , Height: 1.30cm , Length: 23.50cm Weight: 4.439kg ISBN: 9783662496497ISBN 10: 3662496496 Pages: 201 Publication Date: 23 June 2016 Audience: Professional and scholarly , Professional & Vocational Format: Hardback Publisher's Status: Active Availability: Manufactured on demand We will order this item for you from a manufactured on demand supplier. Table of ContentsMolecular Radiobiology: Hypoxia.- Molecular Targeting of Growth Factor Receptor Signaling.- Molecular Targeting of Cell Adhesion Molecules.- Tumor Pathophysiology.- DNA Repair.- Cancer Stem Cells.- Normal Tissue. Biomarkers/Personalized Radiation Oncology: EGFR and other RTKs.- HPV.- Hypoxia.- Study design for Biomarker research in radiation oncology.- Gene expression/system biology. Molecular Imaging in Radiation Oncology:FMISO as a biomarker for clinical radiation oncology.- FDG and beyond.- Molecular imaging techniques beyond PET.ReviewsAuthor InformationMichael Baumann, University of Technology, Dresden, Germany.Mechthild Krause, University of Technology, Dresden, Germany.Nils Cordes, University of Technology, Dresden, Germany. Tab Content 6Author Website:Countries AvailableAll regions |