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OverviewDuring our short time on earth, we all undergo the highly complex process of aging, and with it, we experience the many physiological symptoms. Studies of premature aging have produced a great deal of information that gives some aspects of aging a better understanding. This book explores Werner's syndrome. To some, Werner's syndrome is considered a caricature of aging, but others will find it fascinating that only one mutated human gene (WRN) can bring about a multitude of complicated phenotypes that are usually associated with aging. Full Product DetailsAuthor: Michel LebelPublisher: Springer-Verlag New York Inc. Imprint: Springer-Verlag New York Inc. Edition: Softcover reprint of the original 1st ed. 2004 Dimensions: Width: 15.60cm , Height: 0.90cm , Length: 23.40cm Weight: 0.268kg ISBN: 9781461347668ISBN 10: 1461347661 Pages: 156 Publication Date: 06 November 2012 Audience: Professional and scholarly , Professional & Vocational Format: Paperback Publisher's Status: Active Availability: Manufactured on demand  We will order this item for you from a manufactured on demand supplier. Table of ContentsPreface 1. Clinical Aspects of Werner’s Syndrome: Its Natural History and the Genetics of the Disease 2. Biochemical Roles of RecQ Helicases 3. Biochemical Characterizations of the Werner Syndrome DNA Helicase: Exonuclease 4. Proteins that Interact with the Werner Syndrome Gene Product 5. Sensitivity of Werner’s Syndrome Cells to DNA Damaging Agents: Insights into the Biological Functions of the Werner Protein 6. Yeast RecQ Helicases: Clues to DNA Repair, Genome Stability, and Aging 7. Potential Function of the Werner’s Syndrome Homologue in the African Clawed Frog and the Mouse 8. Proposed Biological Functions for the Werner Syndrome Protein in DNA Metabolism 9. Replicative Senescence, Telomeres, and Werner’s Syndrome IndexReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |
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