Overview

Molecular mechanisms in visual transduction is an intensely studied area in the field of signal transduction research in biological cells. Because the sense of vision plays a primary role in animal biology, and thus has been subject to long evolutionary development, the molecular and cellular mechanisms underlying vision have a high degree of sensitivity and versatility. The aims of visual transduction research are first to determine which molecules participate, and then to understand how they act in concert to produce the exquisite electrical responses of the photoreceptor cells. Since the 1940s it has been known that rod vision begins with the capture of a quantum of energy, a photon, by a visual pigment molecule, rhodopsin. As the function of photon absorption is to convert the visual pigment molecule into a G-protein activating state, the structural details of the visual pigments must be explained from the perspective of their role in activating their specific G-proteins. Thus, chapters 1-3 of this book cover the physico-chemical molecular characteristics of the vertebrate rhodopsins. The following chapters include discussions of related topics in the field.

Full Product Details

Author:   D.G. Stavenga ,  W.J. de Grip ,  E.N. Pugh
Publisher:   Elsevier Science & Technology
Imprint:   North-Holland
Volume:   v. 3
Dimensions:   Width: 15.20cm , Height: 3.20cm , Length: 22.90cm
Weight:   1.260kg
ISBN:  

9780444501028

ISBN 10:   0444501029
Pages:   596
Publication Date:   30 November 2000
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Out of stock  
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Table of Contents

General preface. Preface to volume 3. Contents to volume 3. Contributors to volume 3. Structure and mechanism of vertebrate visual pigments (W.J. DeGrip, K.J. Rothschild). The primary photoreaction of Rhodopsin (R.A. Mathies, J. Lugtenberg). Late photoproducts and signaling states of bovine Rhodopsin (K.P. Hofmann). Ion channels of vertebrate photoreceptors (R.S. Molday, U.B. Kaupp). Phototransduction in vertebrate rods and cones: molecular mechanisms of amplification, recovery and light adaptation (E.N. Pugh Jr., T.D. Lamb). Comparative molecular biology of visual pigments (S.Yokoyama, R. Yokoyama). Invertebrate visual pigments (W. Gartner). Phototransduction mechanisms in microvillar and ciliary photoreceptors of invertebrates (E. Nasi, M. del Pilar Gomez, R. Payne). Genetic dissection of Drosophila phototransduction (B. Minke, R.C. Hardie). Modeling primary visual process in insect photoreceptors (D.G. Stavenga, J. Oberwinkler, M. Postma). Subject Index.

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