Overview

In 1970, Manfred Eigen initiated the study of the origin of self-reproducing systems of macromolecules and their evolution. Large-scale nucleotide sequencing (with computer methods) was introduced from 1977. The authors of this book, the first edition of which appeared (in Russian) in 1985, have been engaged in the research of the evolution of molecular genetic regulatory systems ever since those pioneering years. The book considers many fundamental problems of molecular biology, evolution, molecular genetic organization, the structure and function of macromolecules, always with the underlying motive of developing a unified theory. It describes many original, theoretical results as well as computational methods.

Full Product Details

Author:   Vadim A. Ratner ,  Andrey A. Zharkikh ,  Nikolay Kolchanov ,  Sergey N. Rodin
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Imprint:   Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Edition:   Softcover reprint of hardcover 1st ed. 1996
Volume:   24
Dimensions:   Width: 15.50cm , Height: 2.30cm , Length: 23.50cm
Weight:   0.682kg
ISBN:  

9783642081743

ISBN 10:   3642081746
Pages:   434
Publication Date:   01 December 2010
Audience:   Professional and scholarly ,  Professional and scholarly ,  Professional & Vocational ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

1. Introduction: Approaches and Problems.- 2. Dynamic Properties of Self-Reproducing Molecular Systems: Theoretical Analysis.- 3. The Origin and Evolution of the Genetic Coding-System.- 4. Methods for Studying the Evolution of Macromolecules.- 5. Theoretical Analysis of the Evolution of Genes and Proteins.- 6. The Structural Organization and Evolution of Macromolecules.- 7. The Principles of the Origin and Evolution of Genomes.- 8. Genosystematics.- Addendum.- Conclusion.- References.- References — Addendum.

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