Molecular Biology of Protein Folding, Part B

Author:   P. Michael Conn (Senior Vice President for Research and Associate Provost, Texas Tech Health Sciences Center, TX, USA) ,  Dr. P. Michael Conn
Publisher:   Elsevier Science Publishing Co Inc
Volume:   84
ISBN:  

9780123745958


Pages:   288
Publication Date:   08 December 2008
Format:   Hardback
Availability:   In Print   Availability explained
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Molecular Biology of Protein Folding, Part B


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Approx. 288 pages

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Author:   P. Michael Conn (Senior Vice President for Research and Associate Provost, Texas Tech Health Sciences Center, TX, USA) ,  Dr. P. Michael Conn
Publisher:   Elsevier Science Publishing Co Inc
Imprint:   Academic Press Inc
Volume:   84
Dimensions:   Width: 15.20cm , Height: 2.30cm , Length: 22.90cm
Weight:   0.530kg
ISBN:  

9780123745958


ISBN 10:   0123745950
Pages:   288
Publication Date:   08 December 2008
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print   Availability explained
This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us.

Table of Contents

1. Stability and design of alpha-helical peptides - Andrew Doig 2. Under-wrapped protein folds in disease and epigenetic change - Ariel Fernandez 3. Self-organizing dynamics in protein folding - Bernard S. Gerstman 4. Diffusive models for protein folding - Stephen J Hagen 5. Toward reliable simulations of protein folding, misfolding and aggregation - Ulrich HE Hansmann 6. Single-molecule fluorescence studies of protein folding - Gilad Haran 7. Algorithms for protein folding - Sorin Istrail 8. Use of protein engineering techniques to elucidate protein folding pathways - Sophie Jackson 9. The kinetic stabilities of wild-type and disease-associated mutants of aromatic amino acid hydroxylases. Effect of natural chaperone ligand - Aurora Martinez 10. Chaperone-assisted protein folding in the endoplasmic reticulum - Maurizio Molinari 11. Protein folding over marginal barriers: ensembles, dynamics and stochastics - Victor Munoz

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P. Michael Conn is the Senior Vice President for Research and Associate Provost, Texas Tech Health Sciences Center. He was previously Director of Research Advocacy and Professor of Physiology and Pharmacology, Cell Biology and Development and Obstetrics and Gynecology at Oregon Health and Science University and Senior Scientist of the Oregon National Primate Research Center (ONPRC). He served for twelve years as Special Assistant to the President and Associate Director of the ONPRC. After receiving a B.S. degree and teaching certification from the University of Michigan (1971), a M.S. from North Carolina State University (1973), and a Ph.D. degree from Baylor College of Medicine (1976), Conn did a fellowship at the NIH, then joined the faculty in the Department of Pharmacology, Duke University Medical Center where he was promoted to Associate Professor in 1982. In 1984, he became Professor and Head of Pharmacology at the University of Iowa College of Medicine, a position he held for eleven years. Conn is known for his research in the area of the cellular and molecular basis of action of gonadotropin releasing hormone action in the pituitary and therapeutic approaches that restore misfolded proteins to function. His work has led to drugs that have benefitted humans and animals. He has authored or co-authored over 350 publications in this area and written or edited over 200 books, including texts in neurosciences, molecular biology and endocrinology. Conn has served as the editor of many professional journals and book series (Endocrinology, Journal of Clinical Endocrinology and Metabolism, Endocrine, Methods, Progress in Molecular Biology and Translational Science and Contemporary Endocrinology). Conn served on the National Board of Medical Examiners, including two years as chairman of the reproduction and endocrinology committee. The work of his laboratory has been recognized with a MERIT award from the NIH, the J.J. Abel Award of the American Society for Pharmacology and Experimental Therapeutics, the Weitzman, Oppenheimer and Ingbar Awards of the Endocrine Society, the National Science Medal of Mexico (the Miguel Aleman Prize) and the Stevenson Award of Canada. He is the recipient of the Oregon State Award for Discovery, the Media Award of the American College of Neuropsychopharmacology and was named a distinguished Alumnus of Baylor College of Medicine in 2012. He is an elected member of the Mexican Institute of Medicine and a fellow of the American Association for the Advancement of Science.

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