Molecular and Physiological Mechanisms of Muscle Contraction

Author:   Jean Emile Morel
Publisher:   Taylor & Francis Inc
ISBN:  

9781498725026


Pages:   334
Publication Date:   23 November 2015
Format:   Hardback
Availability:   In Print   Availability explained
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Molecular and Physiological Mechanisms of Muscle Contraction


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Full Product Details

Author:   Jean Emile Morel
Publisher:   Taylor & Francis Inc
Imprint:   CRC Press Inc
Dimensions:   Width: 17.80cm , Height: 2.30cm , Length: 25.40cm
Weight:   0.793kg
ISBN:  

9781498725026


ISBN 10:   1498725023
Pages:   334
Publication Date:   23 November 2015
Audience:   College/higher education ,  College/higher education ,  Postgraduate, Research & Scholarly ,  Tertiary & Higher Education
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print   Availability explained
This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us.

Table of Contents

Introduction: Historical Account and Overview. Materials and Methods. Analysis and Characteristics of Some Major Biophysical, Enzymological and Physiological Phenomena in an Intact Unit Cell During Contraction (Isometric and Isotonic). New and Older Experimental Results and Interpretations. The General Features of the Hybrid Model. Quantitative Data and Calculations, Concerning Short Tetani Under Steady-State Isometric Contraction Conditions, Required for Quantification of the Hybrid Model. Fatigue in One Isometrically Contracting Half-Fibre from a Young Adult Frog, and in Intact and Traditionally Demembranated Fibres of Various Origins: Discussion Based Essentially on the Hybrid Model. Predictive and Explanatory Power of the Hybrid Model: Analysis of Various Problems. In Vitro Motility: Analysis of Experimental Data and Their Interpretations: Movement of Cell Organelles. General Conclusion: From Old Concepts, Old and Recent Experimental Data and Reasoning and New Experimental Results, to a Hybrid Model of Muscle Contraction. Addendum.

Reviews

The monograph is a magisterial work by a scientist who thinks deeply about his subject. The three highlighted topics above only sample a fraction of the subjects covered in depth in the book. The monograph is a rich exploration of the experimental evidence; it is a challenging and sometimes infuriating read because of the selective interpretation of results, but it ofers a valuable opportunity to reassess our understanding of one of the most basic property of animal life-locomotion. --Michael A. Ferenczi, B.Sc., Ph.D., Lee Kong Chain School of Medicine, Singapore, in Journal of Muscle Research and Cell Motility December 2016


Author Information

Jean-Emile Morel earned his PhD in physical chemistry and a second PhD in biophysics at the Ecole Centrale Paris. He was a researcher at the Commissariat à l’Energie Atomique at Saclay, France, where he focused on the complex problem of muscle contraction. He remained at Saclay from 1980 to 2004, becoming professor of bioengineering, biophysics, and cell physiology at the Ecole Centrale Paris and Université Pierre et Marie Curie in Paris, as well as joint director of the DEA course and of the Molecular Biophysics Doctoral School of Université Pierre et Marie Curie. He also founded the Laboratory of Biology at the Ecole Centrale Paris in 1993. Since his retirement in 2004, he has devoted much of his time to reviewing the existing data on muscle contraction and trying to resolve the conundrums of the field.

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