Overview

This volume examines the various aspects of post-transcriptional RNA processing, including biosynthetic, genetic, and functional aspects of nucleotide modification and editing by nucleotide conversion as well as by nucleotide insertion/deletion. It covers techniques for identification and localization of modified nucleosides in RNA and chemical synthesis of RNA with site specific incorporation of natural and/or synthetic modified nucleosides.

Full Product Details

Author:   Henri Grosjean ,  Rob Benne
Publisher:   American Society for Microbiology
Imprint:   American Society for Microbiology
Dimensions:   Width: 27.90cm , Height: 3.40cm , Length: 20.30cm
Weight:   1.744kg
ISBN:  

9781555811334

ISBN 10:   1555811337
Pages:   610
Publication Date:   28 April 1998
Audience:   College/higher education ,  Professional and scholarly ,  Undergraduate ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Unknown
Availability:   Out of stock  

Table of Contents

Historical Perspective on RNA-Nucleoside Modifications; RNA-Modifying and RNA-Editing Enzymes; Detection and Structure Analysis of Modified Nucleosides in RNA by Mass Spectrometry; Incorporation of Modified Nucleosides or Nucleotides in RNA (Nuclear Magnetic Resonance Studies); Biophysical and Conformational Properties of Modified Nucleosides in RNA; Effects of Pseudouridylation on tRNA Hydration and Dynamics; Modulation Role of Modified Nucleotides in Anticodon-Anticodon Interaction; Mechanisms of RNA-Modifying and Editing Enzymes; Structural Basis of Base Exchange by tRNA-Guanine Transglycosylases; Biosynthesis and Functions of Modified Neuclosides in Eurkaryotic mRNA; Posttranscriptional Modifications in the U Small Nuclear RNAs; The Pseudouridine Residues of rRNA; Small Nucleolar RNAs Guide the Ribose Methylations of Eukaryotic rRNAs; Functional Aspects of the Three Modified Nucleotides in Yeast Mitochondrial Large-Subunit rRNA; Regulatory Aspects of rRNA Modifications and Pre-rRNA Processing; Editing by tRNA; RNA Editing by Base Conversion in Plant Organellar RNAs; Apolipoprotein B mRNA Editing; Adenosine-to-Inosine Conversion in mRNA; Nucleoside Deaminases for Cytidine and Adenosine; Mitochondrial mRNA Editing in Kinetoplastid Protozoa; RNA Editing in Physarum Mitochondria; Cotranscriptional Paramyxovirus mRNA Editing; Intracellular Locations of RNA-Modifying Enzymes; Genetics and Regulation of Base Modification in the tRNA and rRNA of Prokaryotes and Eukaryotes; Links Between tRNA Modification and Metabolism and Modified Nucleosides as Tumor Markers; Modified Nucleosides in Translation; Importance of Modified Nucleotides in Replication of Retroviruses, Plant Pararetroviruses and Retrotransposons; Modified Nucleotides Always Were

Reviews

Author Information

Tab Content 6

Author Website:  

Customer Reviews

Recent Reviews

No review item found!

Add your own review!

Countries Available

All regions