Modern Supercritical Fluid Chromatography: Carbon Dioxide Containing Mobile Phases

Author:   Larry M. Miller ,  J. David Pinkston (Indianapolis, Indiana) ,  Larry T. Taylor
Publisher:   John Wiley & Sons Inc
ISBN:  

9781118948392


Pages:   416
Publication Date:   02 January 2020
Format:   Hardback
Availability:   Out of stock   Availability explained
The supplier is temporarily out of stock of this item. It will be ordered for you on backorder and shipped when it becomes available.

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Modern Supercritical Fluid Chromatography: Carbon Dioxide Containing Mobile Phases


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Overview

Explains why modern supercritical fluid chromatography (SFC) is the leading ""green"" analytical and purification separations technology. Modern supercritical fluid chromatography (SFC) is the leading method used to analyze and purify chiral and achiral chemical compounds, many of which are pharmaceuticals, pharmaceutical candidates, and natural products including cannabis-related compounds. This book covers current SFC instrumentation as it relates to greater robustness, better reproducibility, and increased analytical sensitivity. Modern Supercritical Fluid Chromatography: Carbon Dioxide Containing Mobile Phases covers the history, instrumentation, method development and applications of SFC. The authors provided readers with an overview of analytical and preparative SFC equipment, stationary phases, and mobile phase choices. Topics covered include: Milestones of Supercritical Fluid Chromatography; Physical Properties of Supercritical Fluids; Instrumentation for SFC; Detection in SFC; Achiral SFC Method Development; Chiral SFC Method Development; and Preparative Scale SFC. The book also includes highlights of modern applications of SFC in the final chapters—namely pharmaceuticals, consumer products, foods, polymers, petroleum-related mixtures, and cannabis—and discusses the future of SFC. Provides a clear explanation of the physical and chemical properties of supercritical fluids, which gives the reader a better understanding of the basis for improved performance in SFC compared to HPLC and GC Describes the advantages of SFC as a green alternative to HPLC and GC for the analysis of both polar, water-soluble, and non-polar analytes Details both achiral and chiral SFC method development, including modifiers, additives, the impact of temperature and pressure, and stationary phase choices Details why SFC is the premier modern preparative chromatographic technique used to purify components of mixtures for subsequent uses, both from performance and economic perspectives Covers numerous detectors, with an emphasis on SFC-MS, SFC-UV, and SFC-ELSD (evaporative light scattering detection) Describes the application of SFC to numerous high-value application areas Modern Supercritical Fluid Chromatography: Carbon Dioxide Containing Mobile Phases will be of great interest to professionals, students, and professors involved in analytical, bioanalytical, separations science, medicinal, petroleum, and environmental chemistries. It will also appeal to pharmaceutical scientists, natural-product scientists, food and consumer-products scientists, chemical engineers, and managers in these areas.

Full Product Details

Author:   Larry M. Miller ,  J. David Pinkston (Indianapolis, Indiana) ,  Larry T. Taylor
Publisher:   John Wiley & Sons Inc
Imprint:   John Wiley & Sons Inc
Dimensions:   Width: 15.00cm , Height: 2.30cm , Length: 23.10cm
Weight:   0.748kg
ISBN:  

9781118948392


ISBN 10:   1118948394
Pages:   416
Publication Date:   02 January 2020
Audience:   Professional and scholarly ,  College/higher education ,  Professional & Vocational ,  Tertiary & Higher Education
Format:   Hardback
Publisher's Status:   Active
Availability:   Out of stock   Availability explained
The supplier is temporarily out of stock of this item. It will be ordered for you on backorder and shipped when it becomes available.

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LARRY M. MILLER is Principal Scientist at Amgen in Cambridge, MA, and is the author or co-author of more than 30 peer reviewed publications and two book chapters. J. DAVID PINKSTON, PHD, is Technical Services Manager at Archer Daniels Midland in Decatur, IL and the author or co-author of over 60 peer-reviewed publications and book chapters. LARRY T. TAYLOR, PHD, is Emeritus Professor of Chemistry at Virginia Tech in Blacksburg, VA, and the author or co-author of more than 400 peer-reviewed publications, books, and book chapters.

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