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OverviewThe human genome of three billion letters has been sequenced. So have the genomes of thousands of other organisms. With unprecedented resolution, modern technologies are allowing us to peek into the world of genes, biomolecules, and cells - and flooding us with data of immense complexity that we are just barely beginning to understand. A huge gap separates our knowledge of the components of a cell and what is known from our observations of its physiology. The authors have written this graduate textbook to explore what has been done to close this gap of understanding between the realms of molecules and biological processes. They have gathered together illustrative mechanisms and models of gene regulatory networks, DNA replication, the cell cycle, cell death, differentiation, cell senescence, and the abnormal state of cancer cells. The mechanisms are biomolecular in detail, and the models are mathematical in nature. The interdisciplinary presentation will be of interest to both biologists and mathematicians, and every discipline in between. Full Product DetailsAuthor: Baltazar Aguda (Visiting Associate Professor, The Ohio State University) , Avner Friedman (Director, Mathematical Biosciences Institute, The Ohio State University)Publisher: Oxford University Press Imprint: Oxford University Press Dimensions: Width: 17.30cm , Height: 1.20cm , Length: 24.50cm Weight: 0.366kg ISBN: 9780199657506ISBN 10: 0199657505 Pages: 194 Publication Date: 13 September 2012 Audience: College/higher education , Postgraduate, Research & Scholarly Format: Paperback Publisher's Status: Active Availability: To order  Stock availability from the supplier is unknown. We will order it for you and ship this item to you once it is received by us. Table of Contents1: General Introduction 2: From Molecules to a Living Cell 3: Mathematical and Computational Modeling Tools 4: Gene regulatory networks: from DNA to metabolites and back 5: Control of DNA replication in a prokaryote 6: The Eukaryotic Cell Cycle Engine 7: Cell Cycle Control 8: Cell Death 9: Cell Differentiation 10: Cell Aging and Renewal 11: Multiscale Modeling of CancerReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |
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