Overview

The chromosomes of living organisms were once thought to be very stable with changes in genetic content infrequent and generally small. We now know all chromosomes contain a multitude of mobile genetic elements that can change position, cause mutation and proliferate. This study describes how such elements can influence the biology and evolution of all organisms and provides unifying information on the mechanisms of element mobility. Moreover, the book contains methodologies for using mobile genetic elements as tools in the analysis of gene structure and function.

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9780199634040

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clear and perfectly well comprehensible so that all cellular and molecular biologists will take profit of this book, which will look, soon, as the indispensable companion of the every day research. Cellular & Molecular Biology, Vol. 42, No. 3, 1996 I found the book highly readable. The authors have all worked hard to keep their arguments clear and concise and the very comprehensive use of primary references (there are around 500 in the book) is admirable. If you want an up-to-date coverage of the very broad field of mobile genetic elements, you rerally ought to buy this book. Andy Flavell, University of Dundee, Heredity, 77 clearly written and well illustrated ... This book is aimed at those who do not currently work with transposable elements but have an academic interest in them or are thinking about using them. Such readers will find much of interest. Kevin O'Hare, Imperial College of Science, Technology, and Medicine, Science, Vol. 272, May 1996 an excellent overview of mobile genetic elements ... The utility and strength of this book is that mobile genetic elements from a wide diversity of organisms are discussed in a single text. Journal of Heredity 89 (1)

The book is generally clearly written and well illustrated ... . I especially enjoyed, and recommend to all those interested in the history of modern biology, the opening chapter, by James Shapiro. -- Science<br>

`clear and perfectly well comprehensible so that all cellular and molecular biologists will take profit of this book, which will look, soon, as the indispensable companion of the every day research.' Cellular & Molecular Biology, Vol. 42, No. 3, 1996 `I found the book highly readable. The authors have all worked hard to keep their arguments clear and concise and the very comprehensive use of primary references (there are around 500 in the book) is admirable. If you want an up-to-date coverage of the very broad field of mobile genetic elements, you rerally ought to buy this book.' Andy Flavell, University of Dundee, Heredity, 77 `clearly written and well illustrated ... This book is aimed at those who do not currently work with transposable elements but have an academic interest in them or are thinking about using them. Such readers will find much of interest.' Kevin O'Hare, Imperial College of Science, Technology, and Medicine, Science, Vol. 272, May 1996 `an excellent overview of mobile genetic elements ... The utility and strength of this book is that mobile genetic elements from a wide diversity of organisms are discussed in a single text.' Journal of Heredity 89 (1)

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