Overview

The Migraine Brain, edited by David Borsook, Arne May, Peter J. Goadsby, and Richard Hargreaves, makes a major contribution to the field, addressing the increasingly sophisticated neuroimaging techniques that have allowed researchers to begin to define functional and anatomical characteristics of migraine and other less-common types of headache. Of particular focus is how imaging is changing the way we understand migraine. This includes changes in function, structure and chemistry of the migraine brain. Included are sections that focus on particular aspects of migraine, for example the migraine aura: those symptoms that cause visual sensitivity (blinding white light), sensory difficulty (loud noises, painful touch, and hot/cold spells), slurred language, and motor dysfunction. Extensively illustrated throughout, The Migraine Brain provides a general overview of the history of migraine, its pathophysiology, as well as in-depth details on the Clinical Perspectives and the different imaging techniques in use (MR, fMRI, DTI, VBM, PET, fMRI, and MEG). It also includes details on modulation of the brain using such techniques as TMS. The book concludes with a discussion of future uses of imaging in the diagnosis and treatment of migraines and other headaches.A collation of the top thinkers in the field and the only book of its kind, The Migraine Brain is necessary reading for neurologists and neuroscientists.

Full Product Details

Author:   David Borsook (Director, Pain & Analgesia Imaging Neuroscience (P.A.I.N.) Group, McLean Hospital, Masschusetts General Hospital, and Children's Hospital) ,  Arne May (Institut fur Systemische Neurowissenschaften, Zentrum fur Experimentelle Medizin, Universitatsklinikum Hamburg-Eppendorf) ,  Peter J. Goadsby (Director, UCSF Headache Center, Department of Neurology, University of California, San Francisco) ,  Richard Hargreaves (Vice President, Worldwide Discovery Head, Neuroscience, Merck Research Laboratories)
Publisher:   Oxford University Press Inc
Imprint:   Oxford University Press Inc
Dimensions:   Width: 22.30cm , Height: 2.80cm , Length: 28.20cm
Weight:   1.562kg
ISBN:  

9780199754564

ISBN 10:   019975456
Pages:   400
Publication Date:   30 August 2012
Audience:   College/higher education ,  Professional and scholarly ,  Tertiary & Higher Education ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   To order  
Stock availability from the supplier is unknown. We will order it for you and ship this item to you once it is received by us.

Table of Contents

I. Migraine: History Chapter 1: A History of Migraine, Mervyn Eadie II. Neurobiology of the Migraine Brain Chapter 2: Migraine - Some Theories and Controversies, Farooq Maniyar and Peter J. Goadsby Chapter 3: Neural System Changes in Migraine, Peter D. Drummond Chapter 4: Sensitization of Trigeminovascular Pathway: Implications to Migraine Pathophysiology, Rami Burstein and David Borsook Chapter 5: Brain Measures of the Interictal Migraine Brain State (IMBS), Nasim Maleki, Lino Becerra, and David Borsook Chapter 6: From Episodic to Chronic Migraine, Richard B. Lipton and Marcelo E. Bigal Chapter 7: Concomitant Symptoms in Migraine, Arne May & Anne Stankewitz III. Clinical Perspective Chapter 8: Clinical Neuroimaging of Migraine, Randolph W. Evans Chapter 9: Prophylaxis: What Measures?, Stephen Silberstein Chapter 10: Iron Accumulation in Migraine, Inge H. Palm-Meinders, Michel D. Ferrari, Mark C. Kruit Chapter 11 : Migraine and Brain Lesions, Inge H. Palm-Meinders, Michel D. Ferrari, Mark C. Kruit Chapter 12: Clinical Utility of Objective Measures, Franz Riederer, Andreas R. Gantenbein & Peter S. Sandor Chapter 13: Migraine Genes - Clinical and Preclinical Perspectives, Claudia M. Weller, Boukje de Vries, Gisela M Terwindt, Michel D. Ferrari, Joost Haan, and Arn M.J.M. van den Maagdenberg IV. Imaging Migraine Chapter 14: In Search of Future Treatments, Richard Hargreaves and David Dodick Chapter 15: Imaging migraine: A history, Jes Olesen and Peer Tfelt-Hansen Chapter 16: Focus on the Midbrain, Hans-Christoph Diener, Arne May Chapter 17: Diffusion Weighted Imaging in Migraine, Christos Sidiropoulos and Panayiotis D. Mitsias Chapter 18: DIFFUSION TENSOR IMAGING ABNORMALITIES IN MIGRAINE, Maria A. Rocca and Massimo Filippi Chapter 19: Morphometric changes and VBM, Arne May Chapter 20: SURFACE-BASED STRUCTURAL CHANGES IN MIGRAINE, Cristina Granziera Chapter 21: Changing receptors in Migraine state, Genevieve Demarquay and Francois Mauguiere Chapter 22: 15O PET studies in migraine, Marie Denuelle, Pierre Payoux, Nelly Fabre and Gilles Geraud Chapter 23 : Imaging activation in the migraine state, Till Sprenger, Christian Seifert, Peter J. Goadsby Chapter 24: Metabolites and migraine, Caterina Tonon, Giulia Pierangeli, Sabina Cevoli, Pietro Cortelli, Raffaele Lodi Chapter 25: Visual aura, Nouchine Hadjikhani, Maurice B. Vincent Chapter 26: Functional Imaging of the Migraine Brain: New Insights into Brain Dysfunction, Eric A. Moulton Chapter 27: TMS and MEG studies in migraine, Sheena K Aurora, Sidra Saeed, and Susan M Bowyer Chapter 28: Magnetic Resonance Angiography and Migraine, M. Sohail Asghar and Messoud Ashina Chapter 29: Transcranial Magnetic Stimulation (TMS) / Repetitive Transcranial Magnetic Stimulation (rTMS), Magdalena Sarah Volz and Felipe Fregni Chapter 30: Measures of cortical excitability, Gianluca Coppola and Jean Schoenen Chapter 31: Drug Effects on Cortical Excitability, Susan M. Bowyer and Panayiotis D. Mitsias V. Conclusions Chapter 32: Defining the Migraine Phenotype, Todd J. Schwedt and David W. Dodick Chapter 33: The Future of Imaging in Migraine Diagnosis and Treatment, David Borsook and Lino Becerra Chapter 34: Can Imaging Effectively Transform Migraine Treatment?, David Borsook, Arne May, Peter Goadsby, Richard Hargreaves

Reviews

<br> The Migraine Brain - Imaging Structure and Function reviews the astonishing progress that has been made, based on diverse noninvasive imagining technologies, in visualizing the neural basis of a disorder that, not long ago, was essentially invisible. While some features of migraine could be detected through the neurologic exam, the most salient symptoms, including the headache, were characterized largely through subjective report. Although this multi-authored volume focuses on imaging, it provides a relatively broad outline of migraine, making it useful and interesting for readers beyond the specialist. -- Steven E. Hyman, MD, Broad Institute of Harvard and MIT, Cambridge, MA<p><br> It is a superb summary of the explosion of recent research into the origins and causes of migraine. It highlights the many ways in which the migraine brain is different both during and between individual attacks of headache. It is especially timely because until recently we have been dependent upon clinical observation and static imaging techniques for hints about the origins and process of migraine. Now genetic advances and functional imaging techniques, all elegantly summarized by the world-class expert authors of this book, have put us on a fast track to solving the mysteries of migraine. I view this as essential reading for anyone looking for a synthesis of the exciting progress being made in the dynamic field of migraine research. -- Elizabeth Loder, MD, MPH, The John R. Graham Headache Center, Chief, Division of Headache and Pain, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA<p><br>

The Migraine Brain - Imaging Structure and Function reviews the astonishing progress that has been made, based on diverse noninvasive imagining technologies, in visualizing the neural basis of a disorder that, not long ago, was essentially invisible. While some features of migraine could be detected through the neurologic exam, the most salient symptoms, including the headache, were characterized largely through subjective report. Although this multi-authored volume focuses on imaging, it provides a relatively broad outline of migraine, making it useful and interesting for readers beyond the specialist. -- Steven E. Hyman, MD, Broad Institute of Harvard and MIT, Cambridge, MA It is a superb summary of the explosion of recent research into the origins and causes of migraine. It highlights the many ways in which the migraine brain is different both during and between individual attacks of headache. It is especially timely because until recently we have been dependent upon clinical observation and static imaging techniques for hints about the origins and process of migraine. Now genetic advances and functional imaging techniques, all elegantly summarized by the world-class expert authors of this book, have put us on a fast track to solving the mysteries of migraine. I view this as essential reading for anyone looking for a synthesis of the exciting progress being made in the dynamic field of migraine research. -- Elizabeth Loder, MD, MPH, The John R. Graham Headache Center, Chief, Division of Headache and Pain, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA This book is unique in this field. Functional neuroimaging is cutting edge...This book puts functional neuroimaging of the migraine into clinical context. It can and will be used by readers to learn about the migraine brain and the neuroimaging tools available to study it, to apply this knowledge to help patients, and to inspire further research in this field. -- Amaal Jilani Starling, MD, Mayo Clinic Arizona, Doody's The Migraine Brain is an expertly authored and edited compendium of insights into human migraine pathophysiology. The strength of the book is its informative synthesis of an enormous body of literature, accompanied by clinical interpretation by recognized experts in the field. The writing is accessible, and the topics are timely. The Migraine Brain is poised to be a standard reference on the topic of migraine pathophysiology and neuroimaging. -- Jonathan H. Smith, MD, Neurology This book is a major contribution to the study of the migraine headache. ... The editors and the authors of the content in this important volume have provided a service of incalcuable value with the information they provide in this milestone work on the migraine brain. They are to be heartily congratulated for their work in researching and writing for this work, and generously sharing their knowledge, experience, and insight. --Biz India

This book is unique in this field. Functional neuroimaging is cutting edge. It puts functional neuroimaging of the migraine into clinical context. It can and will be used by readers to learn about the migraine brain and the neuroimaging tools available to study it, to apply this knowledge to help patients, and to inspire further research in this field. Doody's Review

Author Information

David Borsook, MD, PhD Director, Pain & Analgesia Imaging Neuroscience (P.A.I.N.) Group McLean Hospital, Masschussetts General Hospital, and Children's Hospital Belmont, MA Arne May, MD, PhD Institut fur Systemische Neurowissenschaften Zentrum fur Experimentelle Medizin Universitatsklinikum Hamburg-Eppendorf Hamburg, Germany Peter Goadsby, MD, PhD Director, UCSF Headache Center Department of Neurology University of California, San Francisco San Francisco, CA Richard Hargreaves, PhD Vice President Worldwide Head of Basic Research Neuroscience Merck Research Laboratories West Point PA

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