Free Delivery Over $100
|
|
|||
|
||||
OverviewFull Product DetailsAuthor: Matthieu Piel , Junsang Doh , Daniel FletcherPublisher: Elsevier Science Publishing Co Inc Imprint: Academic Press Inc Weight: 0.680kg ISBN: 9780128142820ISBN 10: 0128142820 Pages: 247 Publication Date: 29 August 2018 Audience: Professional and scholarly , Professional & Vocational Format: Hardback Publisher's Status: Active Availability: Manufactured on demand  We will order this item for you from a manufactured on demand supplier. Table of ContentsSection 1 - Microfluidics for micro-organisms 1. Temperature control and drug delivery for cell division cycle control in fission yeast 2. H2O2 stress response in budding yeast 3. Antibiotic resistance in bacteria 4. Metabolism in bacteria 5. Fluidized beds for bacterial sorting and amplification Section 2 - Microfluidics for cell culture and cell sorting of mammalian cells 6. Hydrogel microwells 7. Cell sorting with conical filters 8. Directed neuronal cell culture Section 3 - Microfluidics for cell migration 9. Immune cells migration in complexe environments 10. Neutrophiles migration in health and disease 11. Cell guidance by physical cues 12. Stable gradients in gels of extracellular matrix for cancer cell migration Section 4 - Microfluidics for cell mechanics 13. Size based cell sorting and single cell mechanobiology 14. High throughput measure of single cell deformability/stiffness 15. Host-microbe interactions 16. Cell confinement and intracellular crowding Section 5 - Microfluidics for Single cell analytics 17. Quantification of single cell secretion 18. Mechanical cell disruptionReviewsAuthor InformationMatthieu Piel and his team develop microfabricated and microfluidic tools to quantitatively control the physical parameters of the cell's environment and study how cells grow, divide and migrate. The team focused on how physical confinement, geometry and forces affect cell division and cell migration. The general aim of these studies is to draw a line between the physics of the active matter cells are made of and the behavior of cells in the complex environment of tissues, in the context of the immune response and tumor development. Junsang Doh is an associate professor of Mechanical Engineering/Interdisciplinary Bioscience and Bioengineering (I-Bio) in POSTECH, South Korea. Prof. Doh's group develops and utilizes engineering tools such as microfabrication/imaging/mechanics to study fundamental aspects of immune cell behaviors, including synapse-based cell-cell interactions and motility under complex microenvironments, in the context of cancer immunotherapy. Dr. Fletcher and his team develops diagnostic technologies and studies mechanical regulation of membrane and cytoskeleton organization in the context of cell motility, signaling, and host-pathogen interactions. His lab specialize in development of optical microscopy, force microscopy, and microfluidic technologies to understand fundamental organizational principles through both in vitro reconstitution and live cell experiments. Recent work includes investigating the mechano-biochemistry of branched actin network assembly with force microscopy, studying membrane deformation by protein crowding and oligomerization with model membranes, and reconstituting spindle scaling in encapsulated cytoplasmic extracts. The long-term goal of his work is to understand and harness spatial organization for therapeutic applications in cancer and infectious diseases. Tab Content 6Author Website:Countries AvailableAll regions |
||||
