Overview

One of the most promising new approaches for the prevention of HIV transmission, particularly for developing countries, involves topical, self-administered products known as microbicides. The development of microbicides is a long and complicated process, and this volume provides an overview of all the critical areas, from the selection of appropriate candidate molecules and their formulation, preclinical and clinical testing for safety and efficacy, strategies for product registration and finally, issues associated with product launch, distribution and access. The book will prove valuable to both those working in the field and all others who are interested in learning more about this product class, which has the potential to significantly impact the future of this devastating epidemic.

Full Product Details

Author:   Jeremy Nuttall
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Imprint:   Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Edition:   Softcover reprint of the original 1st ed. 2014
Volume:   383
Dimensions:   Width: 15.50cm , Height: 1.00cm , Length: 23.50cm
Weight:   2.993kg
ISBN:  

9783662522615

ISBN 10:   3662522616
Pages:   179
Publication Date:   23 August 2016
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.

Table of Contents

Candidate Microbicides and Their Mechanisms of Action Carolina Herrera and Robin J. Shattock   Microbicide Dosage Forms L.C. Rohan, B. Devlin and H. Yang   Preclinical Safety Evaluation Jonathon D. S. Holt and Jeremy P. Nuttall   Clinical Safety and Pharmacology Trial Christine Mauck, Andrea Thurman and Jill Schwartz   Microbicides for Prevention of HIV Infection: Clinical Efficacy Trials Salim S. Abdool Karim and Cheryl Baxter   Rectal Microbicide Development Ian McGowan and Charlene Dezzutti   Developing Regulatory Strategy for Microbicides Ronald Nardi, Linda Arterburn, and Lisa Carlton   Preparing for Microbicide Introduction, Rollout and Sustained Access Cynthia Woodsong, Tim Farley and Elizabeth McGrory    

Reviews

This book offers a detailed review of essentially all aspects of microbicide development, from the basic science underlying microbicide action, to strategic considerations when implementing international microbicide programs. ... This text could be used as a primer for researchers entering the burgeoning field of microbicide development or for clinicians who provide these agents. (Douglas S. Krakower, Clinical Infectious Diseases CID, Vol. 60, June, 2015)

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