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OverviewThis text examines bioinformatic and genomic approaches for the identification, detection, selection, and validation of antibacterial targets and vaccine candidates. It explores potential pathways for effective infection control, inhibition of antibacterial resistance and acceleration of drug discovery processes and it illustrates the use of pathway tools in a genomics-based drug discovery project. Full Product DetailsAuthor: Thomas J. Dougherty (Pfizer Inc, Groton, Connecticut, USA) , Steven J. Projan (Wyeth-Ayerst Research Laboratories, Cambridge, MA, USA)Publisher: Taylor & Francis Inc Imprint: CRC Press Inc Dimensions: Width: 15.20cm , Height: 1.80cm , Length: 22.90cm Weight: 0.453kg ISBN: 9780824740412ISBN 10: 0824740416 Pages: 264 Publication Date: 14 May 2003 Audience: Professional and scholarly , Professional and scholarly , Professional & Vocational , Postgraduate, Research & Scholarly Format: Hardback Publisher's Status: Active Availability: In Print  This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us. Table of Contents1. Global Aspects of Antibiotic Resistance 2. Genomics of Bacterial Pathogens 3. Bioinformatics, Genomics, and Antimicrobial Drug Discovery 4. The Pathway Tools Software and Its Role in Antimicrobial Drug Discovery 5. Genomic Strategies in Antibacterial Drug Discovery 6. Genomics-Based Approaches to Novel Antimicrobial Target Discovery 7. Pathogenesis Genes as Novel Targets 8. Application of Genomics to the Discovery of New Drugs Against Tuberculosis 9. Phenotype MicroArrays: Their Use in Antibiotic Discovery 10. Microbial Proteomics: New Approaches for Therapeutic Vaccines and Drug Discovery 11. Surrogate Ligand-Based Assay Systems for Discovery of Antibacterial Agents for Genomic Targets 12. Expression Profiling Uses in Antibacterial Chemotherapy Development 13. Using Fungal Genomes for the Discovery, Development, and Clinical Application of Novel and Current Antifungal Therapeutics 14. Genomics in Novel Natural Products GenerationReviewsAuthor InformationDougherty\, Thomas J.; Projan\, Steven J. Tab Content 6Author Website:Countries AvailableAll regions |
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