Overview

Scientists can use molecular profiling microarrays to compare healthy cells with their diseased counterparts and develop gene-specific treatments. Finding the best way to interpret original profiling data into accurate trends, however, continues to drive the development of normalization algorithms and software tools. Methods in Microarray Normalization compiles the most useful and novel techniques for the first time into a single, organized source. Experts in the field provide a diverse view of the mathematical processes that are important in normalizing data and avoiding inherent systematic biases. They also review useful software, including discussions on key algorithms, comparative data, and download locations. The book discusses the use of early normalization techniques for new profiling methods and includes strategies for assessing the utility of various normalization algorithms. It presents the latest microarray innovations from companies such as Agilent, Affymetrix, and GeneGo as well as new normalization methods for protein and CGH arrays, many of which are applicable for antibody, microRNA, methylation, and siRNA arrays. Methods in Microarray Normalization provides scientists with a complete resource on the most effective tools available for maximizing microarray data in biochemical research. Daniel E. Levy, editor of the Drug Discovery Series, is the founder of DEL BioPharma, a consulting service for drug discovery programs. He also maintains a blog that explores organic chemistry.

Full Product Details

Author:   Phillip Stafford ,  Andrew Carmen (Illumina, Inc., San Diego, California, USA) ,  Andrew Carmen (Illumina, Inc., San Diego, California, USA) ,  Ben Bolstad (AffyMetrix Inc., Emeryville, California, USA)
Publisher:   Taylor & Francis Inc
Imprint:   CRC Press Inc
Volume:   10
Dimensions:   Width: 15.60cm , Height: 2.00cm , Length: 23.40cm
Weight:   1.300kg
ISBN:  

9781420052787

ISBN 10:   1420052780
Pages:   320
Publication Date:   31 January 2008
Audience:   Professional and scholarly ,  Professional and scholarly ,  Professional & Vocational ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print  
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Reviews

Methods in Microarray Normalization compiles the most useful and novel techniques for the first time into a single, organized source. Experts in the field provide a diverse view of the mathematical processes that are important in normalizing data and avoiding inherent systematic biases. - In Anticancer Research, July/August 2008, Vol. 28, No. 4A

Methods in Microarray Normalization compiles the most useful and novel techniques for the first time into a single, organized source. Experts in the field provide a diverse view of the mathematical processes that are important in normalizing data and avoiding inherent systematic biases. - In Anticancer Research, July/August 2008, Vol. 28, No. 4A

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Phillip Stafford

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