Novel Concepts in iPSC Disease Modeling

Author:   Alexander Birbrair (Department of Pathology, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil Department of Radiology, Columbia University Medical Center, Medical Center, USA)
Publisher:   Elsevier Science Publishing Co Inc
ISBN:  

9780128238820


Pages:   336
Publication Date:   19 January 2022
Format:   Paperback
Availability:   Not yet available   Availability explained
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Novel Concepts in iPSC Disease Modeling


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Author:   Alexander Birbrair (Department of Pathology, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil Department of Radiology, Columbia University Medical Center, Medical Center, USA)
Publisher:   Elsevier Science Publishing Co Inc
Imprint:   Academic Press Inc
Weight:   0.450kg
ISBN:  

9780128238820


ISBN 10:   0128238828
Pages:   336
Publication Date:   19 January 2022
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Not yet available   Availability explained
This item is yet to be released. You can pre-order this item and we will dispatch it to you upon its release.

Table of Contents

1. Induced Pluripotent Stem Cells: Novel Concepts for Respiratory Disease Modelling 2. iPSC For Modeling of Metabolic and Neurodegenerative Disorders 3. iPSCs for Modeling Open-Angle Glaucoma 4. Patient-Specific Induced Pluripotent Stem Cells for Modeling Amyloid Disease 5. iPSCs for Modeling Choroideremia 6. Applications of human hiPSC and hESC for modeling substance use disorders: Addiction and neurodevelopmental toxicity 7. iPSCs for Modeling Cardiac Sodium Channelopathies 8. iPSCs for Modeling Danon Disease 9. Human induced pluripotent stem cells for Modeling of Niemann-Pick Disease type C1 10. iPSC-based Modeling in Psychiatric Disorders: Opportunities and Challenges 11. Research Applications of iPSCs for Modeling of Spinal Cord Injury 12. iPSCs for Modeling Smith-Magenis Syndrome

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Author Information

Dr. Alexander Birbrair received his bachelor's biomedical degree from Santa Cruz State University in Brazil. He completed his PhD in Neuroscience, in the field of stem cell biology, at the Wake Forest School of Medicine under the mentorship of Osvaldo Delbono. Then, he joined as a postdoc in stem cell biology at Paul Frenette's laboratory at Albert Einstein School of Medicine in New York. In 2016, he was appointed faculty at Federal University of Minas Gerais in Brazil, where he started his own lab. His laboratory is interested in understanding how the cellular components of different tissues function and control disease progression. His group explores the roles of specific cell populations in the tissue microenvironment by using state-of-the-art techniques. His research is funded by the Serrapilheira Institute, CNPq, CAPES, and FAPEMIG. In 2018, Alexander was elected affiliate member of the Brazilian Academy of Sciences (ABC), and, in 2019, he was elected member of the Global Young Academy (GYA), and in 2021, he was elected affiliate member of The World Academy of Sciences (TWAS). He is the Founding Editor and Editor-in-Chief of Current Tissue Microenvironment Reports, and Associate Editor of Molecular Biotechnology. Alexander also serves in the editorial board of several other international journals: Stem Cell Reviews and Reports, Stem Cell Research, Stem Cells and Development, and Histology and Histopathology.

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