Overview

The purpose of this book is to bring together the latest findings on metabolic disorders that are strongly implicated in various critically ill patients. Since the beginning of the 20th century, maintaining the ""milieu intérieur"" has been a major challenge for intensivists. In addition to considerable technological developments in intensive care units, important advances in our understanding of metabolic disorders observed in critically ill patients have been made during the 10 last years. Today, the intensivit can’t ignore these disorders when selecting the most appropriate treatment for an illness.  Cellular metabolic abnormalities are responsible for systems and organ failures, so the modern approach of organ dysfunctions now includes  prevention or treatment of such disorders. This book is a  comprehensive tool, allowing the physician to understand, diagnose and treat these metabolic disorders. Water, electrolyte, acid-base, glycemic and endocrinologic problems, as well as metabolic abnormalities observed in renal, cerebral and hepatic failure are presented in different chapters. The last part of the book is devoted to modern nutritional concepts, the consequences of energy modifications, mitochondrial dysfunction, hypothermia, oxidative stress and ischemia reperfusion, which open the way for new therapies.​

Full Product Details

Author:   Carole Ichai ,  Hervé Quintard ,  Jean-Christophe Orban
Publisher:   Springer International Publishing AG
Imprint:   Springer International Publishing AG
Edition:   Softcover reprint of the original 1st ed. 2018
Weight:   0.988kg
ISBN:  

9783319876986

ISBN 10:   3319876988
Pages:   477
Publication Date:   04 June 2019
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.
Language:   English

Table of Contents

Section 1. Fluid and electrolytes disorders Chapter 1. Water and sodium balances Chapter 2. Sodium disorders Chapter 3. Potassium disorders Chapter 4. Phosphate and calcium disorders Section 2. Acid-base disorders Chapter 5. Interpretation of acid-base disorders Chapter 6. Acidosis : diagnosis and treatment Chapter 7. Alkalosis : diagnosis and treatment Chapter 8. Lactate : metabolism, physiopathology Section 3. Kidney and metabolic disorders Chapter 9. Metabolism et renal functions Chapter 10. Extra-renal removal therapies in acute kidney injury Chapter 11. Strategies for preventing acute kidney failure Section 4. Brain and metabolic disorders Chapter 12. Cerebral metabolism and function Chapter 13. Cerebral ischemia: patholophysiology, diagnosis and treatment Chapter 14. Evaluation of cerebral blood flow in the intensive care unit Section 5. Endocrine disorders in intensive care unit Chapter 15. Acute complications of diabetes Chapter 16. Neuroendocrine dysfunction in the critically ill patients Chapter 17. Hyperglycemia in intensive care unit Section 6. Energetic metabolism, Nutrition.- Chapter 18. Nutritional requirements in intensive care unit Chapter 19. Pharmaconutrition in the critically ill patient Chapter 20. Oxygen, oxidative stress Chapter 21. Energetic metabolism : from the organ to the cell Chapter 22. Ischemia-reperfusion concepts of myocardial preconditionning and postconditioning Chapter 23. Targeted temperature management in severe brain injured patient

Reviews

With the comprehensive and up-to-date references, readers may readily find further information on specific issues. The text is easy to read and understand. ... For those seeking a deeper understanding of metabolic disorders from their pathophysiology to their clinical implications, Metabolic Disorders and Critically Ill Patients will certainly be worth reading. Its appealing didactic structure makes it a valuable tool for teaching and training purposes. (Ashraf A. Dahaba, Anesthesia & Analgesia, Vol. 127 (3), September, 2018)

Author Information

Dr Carole Ichai, MD and PhD, is Professor of Anesthesiology and Intensive Care Medicine at the University of Nice and is the head of the medico surgical Intensive Care Unit at the Saint Roch Hospital. She is a Past-member of the scientific and intensive care unit of the French Society of Anesthesiology and Intensive Care Unit (SFAR). She is the Director of the ""Sud Méditerranée"" European Courses in Anesthesiology and Intensive Care. Her main research interest is all metabolic disturbances and consequences (glycemia disturbances, acid-base water and electrolytes disorders, acute renal failure and hemofiltration) in critically ill patients. Dr Hervé Quintard is a specialist in Anesthesiology and Intensive Care Medicine at the University of Nice and is a full practician of the medico surgical Intensive Care Unit at the Saint Roch Hospital. He is the co-responsible with Pr Ichai of a University Diploma of ""Metabolic Intensive Care"". His main research interest is in the management and metabolic disturbances of cerebral injury with an experimental research (affiliation in a CNRS laboratory) and a clinical one focused on severe head trauma and sub-arachnoid hemorrhage. Dr Jean-Christophe Orban, PhD, is a specialist in Anesthesiology and Intensive Care Medicine at the University of Nice and is a full practician of the medico surgical Intensive Care Unit at the Saint Roch Hospital. He is the co-responsible with Pr Ichai of a University Diploma of ""ICU competences for nurses"". His main research interest is in the metabolic consequences of cardiac arrest, therapeutic hypothermia and mitochondrial dysfunction with an experimental research (affiliation in a INSERM laboratory) and a clinical one.

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