Meselson, Stahl, and the Replication of DNA: "A History of ""The Most Beautiful Experiment in Biology"""

Author:   Frederic Lawrence Holmes
Publisher:   Yale University Press
ISBN:  

9780300085402


Pages:   528
Publication Date:   10 November 2001
Format:   Hardback
Availability:   Manufactured on demand   Availability explained
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Meselson, Stahl, and the Replication of DNA: "A History of ""The Most Beautiful Experiment in Biology"""


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Overview

"In 1957 two young scientists, Matthew Meselson and Frank Stahl, produced a landmark experiment confirming that DNA replicates as predicted by the double helix structure Watson and Crick had recently proposed. It also gained immediate renown as a ""most beautiful"" experiment whose beauty was tied to its simplicity. Yet the investigative path that led to the experiment was anything but simple, Frederic L. Holmes shows in this masterful account of Meselson and Stahl's quest. This book vividly reconstructs the complex route that led to the Meselson-Stahl experiment and provides an inside view of day-to-day scientific research--its unpredictability, excitement, intellectual challenge, and serendipitous windfalls, as well as its frustrations, unexpected diversions away from original plans, and chronic uncertainty. Holmes uses research logs, experimental films, correspondence, and interviews with the participants to record the history of Meselson and Stahl's research, from their first thinking about the problem through the publication of their dramatic results. Holmes also reviews the scientific community's reception of the experiment, the experiment's influence on later investigations, and the reasons for its reputation as an exceptionally beautiful experiment."

Full Product Details

Author:   Frederic Lawrence Holmes
Publisher:   Yale University Press
Imprint:   Yale University Press
Dimensions:   Width: 15.60cm , Height: 0.40cm , Length: 23.50cm
Weight:   0.889kg
ISBN:  

9780300085402


ISBN 10:   0300085400
Pages:   528
Publication Date:   10 November 2001
Audience:   College/higher education ,  Professional and scholarly ,  Undergraduate ,  Postgraduate, Research & Scholarly
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand   Availability explained
We will order this item for you from a manufactured on demand supplier.

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"""Holmes has written a remarkable history of one of molecular biology's most significant experiments. His recreation of a seminal time in the development of the field is masterful and detailed, and it is exciting reading for anyone interested in how experimentation is actually done in a molecular biology laboratory."" David Baltimore, president, California Institute of Technology"


Holmes has written a remarkable history of one of molecular biology's most significant experiments. His recreation of a seminal time in the development of the field is masterful and detailed, and it is exciting reading for anyone interested in how experimentation is actually done in a molecular biology laboratory. David Baltimore, president, California Institute of Technology


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